Wear in molded tibial inserts: Knee simulator study of H1900 and GUR1050 polyethylenes

Hi-fax 1900™ tibial inserts were used in the IB-1 total knee replacement (TKR) beginning 1978, soon followed by the AGC design. Such direct compression molded (DCM) inserts was relatively immune to oxidation. Unfortunately the Hi-fax 1900™ resin (H1900) was taken off the market in year 2004. As an alternate, GUR1050 was introduced in the Vanguard™ TKR. However there appeared to be little or no wear comparisons of molded inserts. Therefore the study aim was to compare wear performance of GUR1050 to the historical H1900. The hypothesis was that Hi-fax and GUR1050 would show comparable wear performance. The Vanguard™ was a posterior-cruciate sacrificing design (Biomet Inc.). All tibial inserts were sterilized by gamma-radiation (3.2 Mrad) under argon. A 6-channel, displacement-controlled knee simulator was used with serum lubricant (protein concentration 20 mg/mL). Wear assessments were by gravimetric methods and linear regression techniques. The gross weight-loss trends over 2.5 Mc duration demonstrated excellent linear behavior with good agreement between TKR sets (<±10%). Fluid sorption artifacts in control represented less than 5% of gross wear magnitudes. Thus suitable corrections could be made in determining net wear. The H1900 and GUR1050inserts demonstrated net wear-rates of 3.6 and 3.4 mm³/Mc, respectively. This difference was not found to be statistically significant. This wear study demonstrated that GUR1050 inserts were indistinguishable from the Hi-fax 1900 in terms of laboratory wear performance, proving our hypothesis. Given the excellent clinical history of DCM Hi-fax 1900, the GUR1050 should be an ideal candidate for TKR.