Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir: A randomized, placebo-controlled trial

Peter L. Havens; Charles B. Stephensen; Rohan Hazra; Patricia M. Flynn; Craig M. Wilson; Brandy Rutledge; James Bethel; Cynthia G. Pan; Leslie R. Woodhouse; Marta D. Van Loan; Nancy Liu; Jorge Lujan-Zilbermann; Alyne Baker; Bill G. Kapogiannis; Kathleen Mulligan

doi:10.1093/cid/cir968

Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir: A randomized, placebo-controlled trial

Peter L. Havens, Charles B. Stephensen, Rohan Hazra, Patricia M. Flynn, Craig M. Wilson, Brandy Rutledge, James Bethel, Cynthia G. Pan, Leslie R. Woodhouse, Marta D. Van Loan, Nancy Liu, Jorge Lujan-Zilbermann, Alyne Baker, Bill G. Kapogiannis, Kathleen Mulligan

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1013-1025
Number of pages	13
Journal	Clinical Infectious Diseases
Volume	54
Issue number	7
DOIs	https://doi.org/10.1093/cid/cir968
State	Published - Apr 1 2012

ASJC Scopus Subject Areas

Microbiology (medical)
Infectious Diseases

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Havens, P. L., Stephensen, C. B., Hazra, R., Flynn, P. M., Wilson, C. M., Rutledge, B., Bethel, J., Pan, C. G., Woodhouse, L. R., Van Loan, M. D., Liu, N., Lujan-Zilbermann, J., Baker, A., Kapogiannis, B. G., & Mulligan, K. (2012). Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir: A randomized, placebo-controlled trial. Clinical Infectious Diseases, 54(7), 1013-1025. https://doi.org/10.1093/cid/cir968

Havens, PL, Stephensen, CB, Hazra, R, Flynn, PM, Wilson, CM, Rutledge, B, Bethel, J, Pan, CG, Woodhouse, LR, Van Loan, MD, Liu, N, Lujan-Zilbermann, J, Baker, A, Kapogiannis, BG & Mulligan, K 2012, 'Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir: A randomized, placebo-controlled trial', Clinical Infectious Diseases, vol. 54, no. 7, pp. 1013-1025. https://doi.org/10.1093/cid/cir968

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title = "Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir: A randomized, placebo-controlled trial",

author = "Havens, {Peter L.} and Stephensen, {Charles B.} and Rohan Hazra and Flynn, {Patricia M.} and Wilson, {Craig M.} and Brandy Rutledge and James Bethel and Pan, {Cynthia G.} and Woodhouse, {Leslie R.} and {Van Loan}, {Marta D.} and Nancy Liu and Jorge Lujan-Zilbermann and Alyne Baker and Kapogiannis, {Bill G.} and Kathleen Mulligan",

note = "Funding Information: This work was supported by the ATN from the National Institutes of Health (U01 HD 040533 and U01 HD 040474) through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (B. Kapogiannis), with supplemental funding from the National Institute on Drug Abuse (N. Borek) and the National Institute of Mental Health (NIMH) (P. Brouwers, S. Allison). The protocol was coendorsed by the IMPAACT Group. Support for IMPAACT was provided by the National Institute of Allergy and Infectious Diseases, NICHD, and NIMH (U01 A1068632). The study was scientifically reviewed by the ATN{\textquoteright}s Therapeutic Leadership Group. Network, scientific and logistical support was provided by the ATN Coordinating Center (C. Wilson, C. Par-tlow) at the University of Alabama at Birmingham. Network operations and analytic support was provided by the ATN Data and Operations Center at Westat, Inc (J. Korelitz, B. Driver). We thank the ATN Community Advisory Board and the youth who participated in the study. Potential conflicts of interest. All authors: No reported conflicts. Funding Information: Financial support. Eight of these sites used their General Clinical Research Center (GCRC)/Pediatric Clinical Research Center (PCRC) for the study; the centers were supported by grants from the GCRC Program of the National Center for Research Resources, National Institutes of Health, Department of Health and Human Services, as follows: Children{\textquoteright}s National Medical Center, M01RR020359; University of Pennsylvania/Children{\textquoteright}s Hospital of Philadelphia, NCRRUL1-RR-024134; University of California, San Francisco, UL1 RR024131; Seattle Children{\textquoteright}s Hospital, UL1-RR025014; Texas Children{\textquoteright}s Hospital and Baylor College of Medicine, M01-RR00188; Boston University Medical Center, UL1-RR02517; and SUNY Stony Brook, M01-RR10710. The Tulane University Health Sciences Center used its Clinical and Translational Research Center (CTRC) for the study; the center was supported in whole or in part by funds provided through the Louisiana Board of Regents RC/EEP (RC/EEP-06).",

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T1 - Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir

T2 - A randomized, placebo-controlled trial

AU - Havens, Peter L.

AU - Stephensen, Charles B.

AU - Hazra, Rohan

AU - Flynn, Patricia M.

AU - Wilson, Craig M.

AU - Rutledge, Brandy

AU - Bethel, James

AU - Pan, Cynthia G.

AU - Woodhouse, Leslie R.

AU - Van Loan, Marta D.

AU - Liu, Nancy

AU - Lujan-Zilbermann, Jorge

AU - Baker, Alyne

AU - Kapogiannis, Bill G.

AU - Mulligan, Kathleen

N1 - Funding Information: This work was supported by the ATN from the National Institutes of Health (U01 HD 040533 and U01 HD 040474) through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (B. Kapogiannis), with supplemental funding from the National Institute on Drug Abuse (N. Borek) and the National Institute of Mental Health (NIMH) (P. Brouwers, S. Allison). The protocol was coendorsed by the IMPAACT Group. Support for IMPAACT was provided by the National Institute of Allergy and Infectious Diseases, NICHD, and NIMH (U01 A1068632). The study was scientifically reviewed by the ATN’s Therapeutic Leadership Group. Network, scientific and logistical support was provided by the ATN Coordinating Center (C. Wilson, C. Par-tlow) at the University of Alabama at Birmingham. Network operations and analytic support was provided by the ATN Data and Operations Center at Westat, Inc (J. Korelitz, B. Driver). We thank the ATN Community Advisory Board and the youth who participated in the study. Potential conflicts of interest. All authors: No reported conflicts. Funding Information: Financial support. Eight of these sites used their General Clinical Research Center (GCRC)/Pediatric Clinical Research Center (PCRC) for the study; the centers were supported by grants from the GCRC Program of the National Center for Research Resources, National Institutes of Health, Department of Health and Human Services, as follows: Children’s National Medical Center, M01RR020359; University of Pennsylvania/Children’s Hospital of Philadelphia, NCRRUL1-RR-024134; University of California, San Francisco, UL1 RR024131; Seattle Children’s Hospital, UL1-RR025014; Texas Children’s Hospital and Baylor College of Medicine, M01-RR00188; Boston University Medical Center, UL1-RR02517; and SUNY Stony Brook, M01-RR10710. The Tulane University Health Sciences Center used its Clinical and Translational Research Center (CTRC) for the study; the center was supported in whole or in part by funds provided through the Louisiana Board of Regents RC/EEP (RC/EEP-06).

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Vitamin D3 decreases parathyroid hormone in HIV-infected youth being treated with tenofovir: A randomized, placebo-controlled trial

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