Vertical sleeve gastrectomy confers metabolic improvements by reducing intestinal bile acids and lipid absorption in mice

Lili Ding, Eryun Zhang, Qiaoling Yang, Lihua Jin, Kyle M. Sousa, Bingning Dong, Yangmeng Wang, Jui Tu, Xiaoxiao Ma, Jingyan Tian, Hongli Zhang, Zhipeng Fang, Ana Guan, Yixin Zhang, Zhengtao Wang, David D. Moore, Li Yang, Wendong Huang

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere2019388118
JournalProceedings of the National Academy of Sciences of the United States of America
Volume118
Issue number6
DOIs
StatePublished - Sep 2021

ASJC Scopus Subject Areas

  • General

Keywords

  • Bariatric surgery
  • Bile acids
  • Cyp27A1
  • Farnesoid X receptor
  • Lipid absorption
  • Humans
  • Diet, High-Fat/adverse effects
  • Mice, Knockout
  • Obesity, Morbid/metabolism
  • Weight Loss/genetics
  • Bile Acids and Salts/biosynthesis
  • Animals
  • Receptors, Cytoplasmic and Nuclear/genetics
  • Cholestanetriol 26-Monooxygenase/genetics
  • Lipid Metabolism/genetics
  • Mice
  • Lipids/genetics
  • Gastrectomy/methods

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