Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance

Ashleigh E. Schaffer, Almira J. Yang, Fabrizio Thorel, Pedro L. Herrera, Maike Sander

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1904-1914
Number of pages11
JournalMolecular Endocrinology
Volume25
Issue number11
DOIs
StatePublished - Nov 1 2011
Externally publishedYes

ASJC Scopus Subject Areas

  • Molecular Biology
  • Endocrinology

Keywords

  • Animals
  • Cell Proliferation
  • Enzyme-Linked Immunosorbent Assay
  • Insulin-Secreting Cells/cytology
  • Fluorescent Antibody Technique
  • Homeodomain Proteins/genetics
  • Immunoblotting
  • Mice, Transgenic
  • Glucose/metabolism
  • Mice

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