Topical thiotepa treatment for recurrent corneal haze after photorefractive keratectomy

Ellen Anderson Penno, Dennis A. Braun, Aasim Kamal, W. Keith Hamilton, Howard V. Gimbel

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To describe the use of topical thiotepa in the treatment of recurrent haze after photorefractive keratectomy (PRK). Setting: Gimbel Eye Centre, Calgary, Alberta, Canada. Methods: Five patients with recurrent haze after myopic PRK were retreated with phototherapeutic keratectomy and topical thiotepa. Before retreatment, the best corrected visual acuity (BCVA) ranged from 20/40 to 20/200. Follow-up ranged from 3 to to 15 months. Results: Haze, uncorrected visual acuity (UCVA), and BCVA improved in all patients. Three eyes had a UCVA of 20/20-2 or better and a BCVA of 20/20-1 or better. The other 2 eyes experienced regression of the myopia and astigmatism and had a BCVA of 20/25-1 or better. Conclusion: Topical thiotepa appeared to be an effective treatment for recurrent corneal haze following myopic PRK.

Original languageEnglish
Pages (from-to)1537-1542
Number of pages6
JournalJournal of Cataract and Refractive Surgery
Volume29
Issue number8
DOIs
StatePublished - Aug 1 2003

ASJC Scopus Subject Areas

  • Surgery
  • Ophthalmology
  • Sensory Systems

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