TNF-α–induced protein 3 is a key player in childhood asthma development and environment-mediated protection

Johanna Krusche; Monika Twardziok; Katharina Rehbach; Andreas Böck; Miranda S. Tsang; Paul C. Schröder; Jörg Kumbrink; Thomas Kirchner; Yuhan Xing; Josef Riedler; Jean Charles Dalphin; Juha Pekkanen; Roger Lauener; Marjut Roponen; Jing Li; Chun K. Wong; Gary W.K. Wong; Bianca Schaub; Markus Ege; Martin Depner; Sabina Illi; Georg J. Loss; Harald Renz; Petra I. Pfefferle; Michael Kabesch; Jon Genuneit; Anne M. Karvonen; Anne Hyvärinen; Pirkka V. Kirjavainen; Sami Remes; Charlotte Braun-Fahrländer; Caroline Roduit; Remo Frei; Vincent Kaulek; Marie Laure Dalphin; Amandine Divaret-Chauveau; Gert Doekes

doi:10.1016/j.jaci.2019.07.029

TNF-α–induced protein 3 is a key player in childhood asthma development and environment-mediated protection

Johanna Krusche
, Monika Twardziok
, Katharina Rehbach
, Andreas Böck
, Miranda S. Tsang
, Paul C. Schröder
, Jörg Kumbrink
, Thomas Kirchner
, Yuhan Xing
, Josef Riedler
, Jean Charles Dalphin
, Juha Pekkanen
, Roger Lauener
, Marjut Roponen
, Jing Li
, Chun K. Wong
, Gary W.K. Wong
, Bianca Schaub
, Markus Ege
, Martin Depner

Sabina Illi, Georg J. Loss, Harald Renz, Petra I. Pfefferle, Michael Kabesch, Jon Genuneit, Anne M. Karvonen, Anne Hyvärinen, Pirkka V. Kirjavainen, Sami Remes, Charlotte Braun-Fahrländer, Caroline Roduit, Remo Frei, Vincent Kaulek, Marie Laure Dalphin, Amandine Divaret-Chauveau, Gert Doekes

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1684-1696.e12
Journal	The Journal of Allergy and Clinical Immunology
Volume	144
Issue number	6
DOIs	https://doi.org/10.1016/j.jaci.2019.07.029
State	Published - Dec 2019
Externally published	Yes

ASJC Scopus Subject Areas

Immunology and Allergy
Immunology

Keywords

A20
LPS
TNFAIP3
asthma
childhood
environment
farming
immune development
inflammatory
protection
Prospective Studies
Humans
Child, Preschool
Infant
Male
Asthma/blood
Biomarkers/blood
Female
Child
Infant, Newborn
Cross-Sectional Studies
Gene Expression Regulation
Toll-Like Receptor 4/blood
Tumor Necrosis Factor alpha-Induced Protein 3/blood
Longitudinal Studies
Environmental Exposure/adverse effects

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10.1016/j.jaci.2019.07.029

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Krusche, J., Twardziok, M., Rehbach, K., Böck, A., Tsang, M. S., Schröder, P. C., Kumbrink, J., Kirchner, T., Xing, Y., Riedler, J., Dalphin, J. C., Pekkanen, J., Lauener, R., Roponen, M., Li, J., Wong, C. K., Wong, G. W. K., Schaub, B., Ege, M., ... Doekes, G. (2019). TNF-α–induced protein 3 is a key player in childhood asthma development and environment-mediated protection. The Journal of Allergy and Clinical Immunology, 144(6), 1684-1696.e12. https://doi.org/10.1016/j.jaci.2019.07.029

Krusche, J, Twardziok, M, Rehbach, K, Böck, A, Tsang, MS, Schröder, PC, Kumbrink, J, Kirchner, T, Xing, Y, Riedler, J, Dalphin, JC, Pekkanen, J, Lauener, R, Roponen, M, Li, J, Wong, CK, Wong, GWK, Schaub, B, Ege, M, Depner, M, Illi, S, Loss, GJ, Renz, H, Pfefferle, PI, Kabesch, M, Genuneit, J, Karvonen, AM, Hyvärinen, A, Kirjavainen, PV, Remes, S, Braun-Fahrländer, C, Roduit, C, Frei, R, Kaulek, V, Dalphin, ML, Divaret-Chauveau, A & Doekes, G 2019, 'TNF-α–induced protein 3 is a key player in childhood asthma development and environment-mediated protection', The Journal of Allergy and Clinical Immunology, vol. 144, no. 6, pp. 1684-1696.e12. https://doi.org/10.1016/j.jaci.2019.07.029

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title = "TNF-α–induced protein 3 is a key player in childhood asthma development and environment-mediated protection",

keywords = "A20, LPS, TNFAIP3, asthma, childhood, environment, farming, immune development, inflammatory, protection, Prospective Studies, Humans, Child, Preschool, Infant, Male, Asthma/blood, Biomarkers/blood, Female, Child, Infant, Newborn, Cross-Sectional Studies, Gene Expression Regulation, Toll-Like Receptor 4/blood, Tumor Necrosis Factor alpha-Induced Protein 3/blood, Longitudinal Studies, Environmental Exposure/adverse effects",

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AU - Krusche, Johanna

AU - Twardziok, Monika

AU - Rehbach, Katharina

AU - Böck, Andreas

AU - Tsang, Miranda S.

AU - Schröder, Paul C.

AU - Kumbrink, Jörg

AU - Kirchner, Thomas

AU - Xing, Yuhan

AU - Riedler, Josef

AU - Dalphin, Jean Charles

AU - Pekkanen, Juha

AU - Lauener, Roger

AU - Roponen, Marjut

AU - Li, Jing

AU - Wong, Chun K.

AU - Wong, Gary W.K.

AU - Schaub, Bianca

AU - Ege, Markus

AU - Depner, Martin

AU - Illi, Sabina

AU - Loss, Georg J.

AU - Renz, Harald

AU - Pfefferle, Petra I.

AU - Kabesch, Michael

AU - Genuneit, Jon

AU - Karvonen, Anne M.

AU - Hyvärinen, Anne

AU - Kirjavainen, Pirkka V.

AU - Remes, Sami

AU - Braun-Fahrländer, Charlotte

AU - Roduit, Caroline

AU - Frei, Remo

AU - Kaulek, Vincent

AU - Dalphin, Marie Laure

AU - Divaret-Chauveau, Amandine

AU - Doekes, Gert

PY - 2019/12

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KW - asthma

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KW - environment

KW - farming

KW - immune development

KW - inflammatory

KW - protection

KW - Prospective Studies

KW - Humans

KW - Child, Preschool

KW - Infant

KW - Male

KW - Asthma/blood

KW - Biomarkers/blood

KW - Female

KW - Child

KW - Infant, Newborn

KW - Cross-Sectional Studies

KW - Gene Expression Regulation

KW - Toll-Like Receptor 4/blood

KW - Tumor Necrosis Factor alpha-Induced Protein 3/blood

KW - Longitudinal Studies

KW - Environmental Exposure/adverse effects

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IS - 6

ER -

TNF-α–induced protein 3 is a key player in childhood asthma development and environment-mediated protection

ASJC Scopus Subject Areas

Keywords

Access to Document

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