Thyroid-brain Crosstalk

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Abstract

The evidence clearly demonstrates that there is functional crosstalk between the brain and the thyroid. Thyroid hormones have very powerful influences on microglia cells and neuronal neurotransmitter pathways. This is no surprise since individuals with thyroid disorders develop a vast list of neurological, mood, and cognitive symptoms. There is also clear evidence that neurotransmitters are important centrally for the modulation of the hypothalamus-pituitary-thyroid axis. In this paper, a review of these interactions will be divided by interrelationships that include microglia, serotonin, acetylcholine, GABA, and dopamine. 
Original languageAmerican English
JournalFunctional Neurology, Rehabilitation, and Ergonomics
Volume1
StatePublished - 2009

Disciplines

  • Physiology

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