The Use of Seprafilm as a Biological Barrier in Flap Delay

Andrew L. Blount; Adam K. Boettcher; Andrea Van-Pelt; Kerby C. Oberg; Ewa Komorowska-Timek

doi:10.1097/01.prs.0000406318.25436.e4

The Use of Seprafilm as a Biological Barrier in Flap Delay

Andrew L. Blount, Adam K. Boettcher, Andrea Van-Pelt, Kerby C. Oberg, Ewa Komorowska-Timek

Anatomy Division

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Abstract

INTRODUCTION: Seprafilm is a bioresorbable hyaluronatecarboxymethylcellulose membrane used to prevent adhesion formation in abdominal and pelvic surgery1-3. The clinical efficacy of Seprafilm has been attributed to its properties as a non-immunologic barrier. We experimentally investigated the role of Seprafilm in preventing reactive fibrosis around a rat implant and in delayed flaps.

Original language	American English
Journal	Plastic and Reconstructive Surgery
Volume	128
DOIs	https://doi.org/10.1097/01.prs.0000406318.25436.e4
State	Published - Oct 2011

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Medicine and Health Sciences
Surgery

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The Use of Seprafilm as a Biological Barrier in Flap Delay

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