The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity

Kam Tong Leung; Karen Li; Yorky Tsin Sik Wong; Kathy Yuen Yee Chan; Xiao-Bing Zhang; Alex Wing Kwan Leung; Tak Yeung Leung; Kam Sze Tsang; Pak Cheung Ng; Chi Kong Li; Xiaobing Zhang

The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity

Kam Tong Leung
, Karen Li
, Yorky Tsin Sik Wong
, Kathy Yuen Yee Chan
, Xiao-Bing Zhang
, Alex Wing Kwan Leung
, Tak Yeung Leung
, Kam Sze Tsang
, Pak Cheung Ng
, Chi Kong Li
, Xiaobing Zhang

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Blood
Volume	126
State	Published - Dec 3 2015

Disciplines

Biology
Molecular Biology
Oncology
Immunology and Infectious Disease

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@article{b8c015a4f7a1452881ab9c990b8001bb,

title = "The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity",

author = "Leung, \{Kam Tong\} and Karen Li and Wong, \{Yorky Tsin Sik\} and Chan, \{Kathy Yuen Yee\} and Xiao-Bing Zhang and Leung, \{Alex Wing Kwan\} and Leung, \{Tak Yeung\} and Tsang, \{Kam Sze\} and Ng, \{Pak Cheung\} and Li, \{Chi Kong\} and Xiaobing Zhang",

note = "Migration, homing and engraftment of hematopoietic stem/progenitor cells depend critically on the SDF-1/CXCR4 axis. We previously identified the tetraspanin CD9 as a downstream signal of this axis, and it regulates short-term homing of cord blood (CB) CD34+ cells (Leung et al, Blood , 2011).",

year = "2015",

month = dec,

day = "3",

language = "American English",

volume = "126",

journal = "Blood",

}

TY - JOUR

T1 - The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity

AU - Leung, Kam Tong

AU - Li, Karen

AU - Wong, Yorky Tsin Sik

AU - Chan, Kathy Yuen Yee

AU - Zhang, Xiao-Bing

AU - Leung, Alex Wing Kwan

AU - Leung, Tak Yeung

AU - Tsang, Kam Sze

AU - Ng, Pak Cheung

AU - Li, Chi Kong

AU - Zhang, Xiaobing

N1 - Migration, homing and engraftment of hematopoietic stem/progenitor cells depend critically on the SDF-1/CXCR4 axis. We previously identified the tetraspanin CD9 as a downstream signal of this axis, and it regulates short-term homing of cord blood (CB) CD34+ cells (Leung et al, Blood , 2011).

PY - 2015/12/3

Y1 - 2015/12/3

UR - http://www.bloodjournal.org/content/126/23/1169?sso-checked=true

M3 - Article

VL - 126

JO - Blood

JF - Blood

ER -

The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity

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