The Effects of Omega‐3 Supplementation on the Lipid Profile and Adipose Indices in Hispanics with Type 2 Diabetes Mellitus

Toni Jehi, Christy Veronica Mota, W. Lawrence Beeson, Anthony Firek, Zaida R Cordero-MacIntyre, Marino De Leon

Research output: Contribution to journalMeeting abstractpeer-review

Abstract

Background Diabetes mellitus (DM) is considered a serious affliction that highly augments the risk for serious health complications. Evidence is suggesting a role of n-3 polyunsaturated fatty acids (PUFAs) on improving the lipid profile and adipose indices in patients with type 2 DM (DM2). However, this association hasn't been probed much in underserved populations. Thus, the objective of this study was to investigate the effect of the diabetes education program, En Balance Plus, on lipid profiles and adipose indices among Hispanic adults with DM2, using supplemental fish oil. Methods Subjects (n=40) consumed a daily intake of 2000 milligrams of omega 3 fish oil in capsule form for the whole 3-month study. At baseline and after the intervention, comprehensive assessments were conducted to evaluate the health status, dietary habits and total and regional body compositions of the subjects. During analysis, non-parametric tests were utilized to conduct the comparisons. Results There was a significant decrease in median glucose levels (-4.5 mg/dL, p=0.021), hemoglobin A1c (-0.1%; p = 0.001), trunk fat (-1%; p = 0.0134), and total fat (-0.50%; p = 0.0452). As for the changes in cholesterol levels, the only significant differences were observed in LDL(reduced by 5 mg/dL; p= 0.011) Conclusion The omega-3 supplementation for Hispanic patients in the En Balance Plus program contributed to significant attenuation in LDL cholesterol, an improvement in glycemic control, and a decrease in trunk and total fat. Further investigations should be conducted to assess the long term effects of this intervention.
Original languageAmerican English
JournalThe FASEB Journal
Volume32
Issue numberS1
DOIs
StatePublished - Apr 2018

Disciplines

  • Biology
  • Endocrinology, Diabetes, and Metabolism
  • Internal Medicine
  • Endocrinology
  • Dietetics and Clinical Nutrition

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