TY - JOUR
T1 - The Effects of Omega‐3 Supplementation on the Lipid Profile and Adipose Indices in Hispanics with Type 2 Diabetes Mellitus
AU - Jehi, Toni
AU - Mota, Christy Veronica
AU - Beeson, W. Lawrence
AU - Firek, Anthony
AU - Cordero-MacIntyre, Zaida R
AU - De Leon, Marino
N1 - If the address matches an existing account you will receive an email with instructions to reset your password
PY - 2018/4
Y1 - 2018/4
N2 - Background Diabetes mellitus (DM) is considered a serious affliction that highly augments the risk for serious health complications. Evidence is suggesting a role of n-3 polyunsaturated fatty acids (PUFAs) on improving the lipid profile and adipose indices in patients with type 2 DM (DM2). However, this association hasn't been probed much in underserved populations. Thus, the objective of this study was to investigate the effect of the diabetes education program, En Balance Plus, on lipid profiles and adipose indices among Hispanic adults with DM2, using supplemental fish oil. Methods Subjects (n=40) consumed a daily intake of 2000 milligrams of omega 3 fish oil in capsule form for the whole 3-month study. At baseline and after the intervention, comprehensive assessments were conducted to evaluate the health status, dietary habits and total and regional body compositions of the subjects. During analysis, non-parametric tests were utilized to conduct the comparisons. Results There was a significant decrease in median glucose levels (-4.5 mg/dL, p=0.021), hemoglobin A1c (-0.1%; p = 0.001), trunk fat (-1%; p = 0.0134), and total fat (-0.50%; p = 0.0452). As for the changes in cholesterol levels, the only significant differences were observed in LDL(reduced by 5 mg/dL; p= 0.011) Conclusion The omega-3 supplementation for Hispanic patients in the En Balance Plus program contributed to significant attenuation in LDL cholesterol, an improvement in glycemic control, and a decrease in trunk and total fat. Further investigations should be conducted to assess the long term effects of this intervention.
AB - Background Diabetes mellitus (DM) is considered a serious affliction that highly augments the risk for serious health complications. Evidence is suggesting a role of n-3 polyunsaturated fatty acids (PUFAs) on improving the lipid profile and adipose indices in patients with type 2 DM (DM2). However, this association hasn't been probed much in underserved populations. Thus, the objective of this study was to investigate the effect of the diabetes education program, En Balance Plus, on lipid profiles and adipose indices among Hispanic adults with DM2, using supplemental fish oil. Methods Subjects (n=40) consumed a daily intake of 2000 milligrams of omega 3 fish oil in capsule form for the whole 3-month study. At baseline and after the intervention, comprehensive assessments were conducted to evaluate the health status, dietary habits and total and regional body compositions of the subjects. During analysis, non-parametric tests were utilized to conduct the comparisons. Results There was a significant decrease in median glucose levels (-4.5 mg/dL, p=0.021), hemoglobin A1c (-0.1%; p = 0.001), trunk fat (-1%; p = 0.0134), and total fat (-0.50%; p = 0.0452). As for the changes in cholesterol levels, the only significant differences were observed in LDL(reduced by 5 mg/dL; p= 0.011) Conclusion The omega-3 supplementation for Hispanic patients in the En Balance Plus program contributed to significant attenuation in LDL cholesterol, an improvement in glycemic control, and a decrease in trunk and total fat. Further investigations should be conducted to assess the long term effects of this intervention.
UR - https://www.fasebj.org/doi/10.1096/fasebj.2018.32.1_supplement.812.41
UR - https://www.fasebj.org/doi/10.1096/fasebj.30.1_supplement.901.20
U2 - 10.1096/FASEBJ.2018.32.1_SUPPLEMENT.812.41
DO - 10.1096/FASEBJ.2018.32.1_SUPPLEMENT.812.41
M3 - Meeting abstract
VL - 32
JO - The FASEB Journal
JF - The FASEB Journal
IS - S1
ER -