TY - JOUR
T1 - The effect of non-exercise activity thermogenesis on subjects with metabolic syndrome - A proof of concept study in Qatar
AU - Hammoudeh, Samer
AU - Bener, Abdulbari
AU - Zirie, Mahmoud
AU - Al-Hamaq, Abdullah
AU - Chandra, Prem
AU - Moses, Olivia
AU - Dos Santos, Hildemar
AU - Tonstad, Serena
N1 - Publisher Copyright:
© 2013 Hammoudeh, Bener, Zirie, Al-Hamaq, Chandra, Moses, Dos Santos, Tonstad, licensee Bloomsbury Qatar Foundation Journals.
PY - 2013/6/1
Y1 - 2013/6/1
N2 - Metabolic syndrome is a cluster of metabolic abnormalities that increases the risk of cardiovascular disease and type 2 diabetes. Total human energy expenditure is divided into three major components; resting metabolic rate, thermic effect of food, and activity thermogenesis which is divided into exercise and non exercise activity thermogenesis (NEAT). In this study, NEAT was used as a lifestyle intervention on subjects with metabolic syndrome. 200 eligible patients from the Diabetes and Endocrinology Department at Hamad Medical Hospital in Doha, Qatar were assigned to an intervention (n = 100) or control (n = 100) group and followed for one year. The intervention group was advised to practice NEAT enhancing activities, while the control group was not advised about NEAT. Measurements of waist circumference, weight, BMI, blood pressure, glucose and lipid profile were assessed at baseline, six months and 1 year. After 1 year 52 intervention and 55 control subjects completed the study. The results revealed no statistically significant differences in metabolic syndrome components between the two randomized groups. The amount of recommended NEAT activity appears to have been too small to influence study outcomes. Future studies in similar populations may need to consider the high dropout rate, and use of incentives or other interventions to increase compliance and retention.
AB - Metabolic syndrome is a cluster of metabolic abnormalities that increases the risk of cardiovascular disease and type 2 diabetes. Total human energy expenditure is divided into three major components; resting metabolic rate, thermic effect of food, and activity thermogenesis which is divided into exercise and non exercise activity thermogenesis (NEAT). In this study, NEAT was used as a lifestyle intervention on subjects with metabolic syndrome. 200 eligible patients from the Diabetes and Endocrinology Department at Hamad Medical Hospital in Doha, Qatar were assigned to an intervention (n = 100) or control (n = 100) group and followed for one year. The intervention group was advised to practice NEAT enhancing activities, while the control group was not advised about NEAT. Measurements of waist circumference, weight, BMI, blood pressure, glucose and lipid profile were assessed at baseline, six months and 1 year. After 1 year 52 intervention and 55 control subjects completed the study. The results revealed no statistically significant differences in metabolic syndrome components between the two randomized groups. The amount of recommended NEAT activity appears to have been too small to influence study outcomes. Future studies in similar populations may need to consider the high dropout rate, and use of incentives or other interventions to increase compliance and retention.
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U2 - 10.5339/qmj.2013.3
DO - 10.5339/qmj.2013.3
M3 - Article
SN - 0253-8253
VL - 2013
SP - 12
EP - 18
JO - Qatar Medical Journal
JF - Qatar Medical Journal
IS - 1
ER -