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The Effect of Bacillus Coagulans and Galactomannans on the Quality of Life of Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Clinical Trial

Research output: Contribution to journalArticlepeer-review

Abstract

Aim/Background: The purpose of this study was to examine the effect of probiotics and prebiotics (LactoWise®) on the quality of life (QOL) of morbidly obese patients undergoing laparoscopic sleeve gastrectomy (LSG) using the Gastrointestinal Quality of Index (GIQLI). Methods: Study was made of 60 consecutive patients undergoing LSG, who were randomized into two groups, one of which took LactoWise® and the other a placebo. The LactoWise® group received 4.5 billion live cells of Bacillus coagulans and galactomannans (300 mg) in capsule form, and the placebo group received 600 mg of calcium citrate yielding 126 mg of elemental calcium, in identical capsules, daily for 3 months post-surgery. The participants completed the GIQLI prior to surgery at their pre-operation consultation and 3 times post-surgery, at 2 and 6 weeks and at 3 months. Results: A total of 40 patients, with a mean age of 48.0±12.7 years and body mass index (BMI) of 46.2 ±8.0 kg/m 2 completed the study. In both the group taking LactoWise® and the placebo group, following surgery a significant improvement in QOL, according to the median scores on GIQLI was recorded over time (p
Original languageAmerican English
Pages (from-to)121-126
Number of pages6
JournalHellenic Journal of Surgery
Volume90
DOIs
StatePublished - May 1 2018

Disciplines

  • Medicine and Health Sciences
  • Surgery

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