The cytoplasmic dynein associated protein NDE1 regulates osteoclastogenesis by modulating M-CSF and RANKL signaling pathways

Bhaba K. Das, Jyoti Gogoi, Aarthi Kannan, Ling Gao, Weirong Xing, Subburaman Mohan, Haibo Zhao

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number13
JournalCells
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2022
Externally publishedYes

ASJC Scopus Subject Areas

  • General Biochemistry,Genetics and Molecular Biology

Keywords

  • Bone remodeling
  • Bone resorption
  • Cytoplasmic dynein
  • NDE1
  • NDEL1
  • Osteoclast
  • Bone Marrow/pathology
  • Actin Cytoskeleton/metabolism
  • Cell Proliferation
  • Homeostasis
  • Cytoplasmic Dyneins/metabolism
  • Macrophage Colony-Stimulating Factor/metabolism
  • Cell Differentiation
  • Bone and Bones/pathology
  • RANK Ligand/metabolism
  • Osteoclasts/metabolism
  • Signal Transduction
  • Cell Survival
  • Mice, Inbred C57BL
  • Bone Resorption/pathology
  • Mice, Knockout
  • Microtubules/metabolism
  • Animals
  • Mice
  • Osteogenesis
  • Microtubule-Associated Proteins/metabolism
  • Monocytes/metabolism

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