Technical Aspects and Clinical Limitations of Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations

Ashok Agarwal; Ala’a Farkouh; Ramadan Saleh; Taha Abo Almagd Abdel Meguid Hamoda; Gianmaria Salvio; Florence Boitrelle; Ahmed M. Harraz; Ramy Abou Ghayda; Parviz Kavoussi; Murat Gül; Tuncay Toprak; Giorgio Ivan Russo; Damayanthi Durairajanayagam; Amarnath Rambhatla; Ponco Birowo; Rossella Cannarella; Nguyen Ho Vinh Phuoc; Armand Zini; Mohamed Arafa; Christine Wyns; Kelton Tremellen; Selçuk Sarıkaya; Sheena Lewis; Donald P. Evenson; Edmund Ko; Aldo E. Calogero; Fahmi Bahar; Marlon Martínez; Rafael F. Ambar; Giovanni M. Colpi; Mustafa Emre Bakircioglu; Ralf Henkel; Hussein Kandil; Ege Can Serefoglu; Abdullah Alfakhri; Akira Tsujimura; Alireza Kheradmand; Angelo Marino; Aram Adamyan; Birute Zilaitiene; Cevahir Ozer; Edoardo Pescatori; Paraskevi Vogiatzi; Gian Maria Busetto; Giancarlo Balercia; Haitham Elbardisi; Hamed Akhavizadegan; Hesamoddin Sajadi; Hisanori Taniguchi; Hyun Jun Park; Israel Maldonado Rosas; Mohamed Al-Marhoon; Mohammad Ali Sadighi Gilani; Naif Alhathal; Nguyen Quang; Germar Michael Pinggera; Priyank Kothari; Sava Micic; Sheryl Homa; Tran Quang Tien Long; Wael Zohdy; Widi Atmoko; Wael Ibrahim; Marjan Sabbaghian; Saad Mohammed Abumelha; Eric Chung; Muhammet Rasit Ugur; Mehmet Serkan Ozkent; Osama Selim; Mahsa Darbandi; Shinichiro Fukuhara; Mounir Jamali; Jean de la Rosette; Shinnosuke Kuroda; Ryan P. Smith; Aykut Baser; Arif Kalkanli; Nicholas N. Tadros; Kaan Aydos; Tiago Cesar Mierzwa; Kareim Khalafalla; Vineet Malhotra; Mohamad Moussa; Federica Finocchi; Rinaldo Indra Rachman; Carlo Giulioni; Tomer Avidor-Reiss; Oguzhan Kahraman; Gökhan Çeker; Cătălina Zenoaga-Barbăroșie; Trenton L. Barrett; Mehmet Yilmaz; Ates Kadioglu; Sunil Jindal; Huda Omran; Kadir Bocu; Vilvapathy Senguttuvan Karthikeyan; Giorgio Franco; Jesús Fernando Solorzano; Ranjit B. Vishwakarma; Eko Arianto; Nicolas Garrido; Divyanu Jain; Nazim Gherabi; Ioannis Sokolakis; Ayad Palani; Gokhan Calik; Deniz Kulaksiz; Vaida Simanaviciene; Mara Simopoulou; Nur Dokuzeylül Güngör; Gideon Blecher; Marco Falcone; Davor Jezek; Mirko Preto; Edouard Amar; Tan V. Le; Sun Tae Ahn; Andri Rezano; Keerti Singh; Lucia Rocco; Missy Savira; Osvaldo Rajmil; Sara Darbandi; Emrullah Sogutdelen; Luca Boeri; Guadalupe Hernández; Lukman Hakim; Yoshiharu Morimoto; Andrian Japari; Nikolaos Sofikitis; Baris Altay; Asli Metin Mahmutoglu; Manaf Al Hashimi; Imad Ziouziou; Christina Anagnostopoulou; Haocheng Lin; Rupin Shah

doi:10.5534/wjmh.230076

Technical Aspects and Clinical Limitations of Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations

Ashok Agarwal
, Ala’a Farkouh
, Ramadan Saleh
, Taha Abo Almagd Abdel Meguid Hamoda
, Gianmaria Salvio
, Florence Boitrelle
, Ahmed M. Harraz
, Ramy Abou Ghayda
, Parviz Kavoussi
, Murat Gül
, Tuncay Toprak
, Giorgio Ivan Russo
, Damayanthi Durairajanayagam
, Amarnath Rambhatla
, Ponco Birowo
, Rossella Cannarella
, Nguyen Ho Vinh Phuoc
, Armand Zini
, Mohamed Arafa
, Christine Wyns

Kelton Tremellen, Selçuk Sarıkaya, Sheena Lewis, Donald P. Evenson, Edmund Ko, Aldo E. Calogero, Fahmi Bahar, Marlon Martínez, Rafael F. Ambar, Giovanni M. Colpi, Mustafa Emre Bakircioglu, Ralf Henkel, Hussein Kandil, Ege Can Serefoglu, Abdullah Alfakhri, Akira Tsujimura, Alireza Kheradmand, Angelo Marino, Aram Adamyan, Birute Zilaitiene, Cevahir Ozer, Edoardo Pescatori, Paraskevi Vogiatzi, Gian Maria Busetto, Giancarlo Balercia, Haitham Elbardisi, Hamed Akhavizadegan, Hesamoddin Sajadi, Hisanori Taniguchi, Hyun Jun Park, Israel Maldonado Rosas, Mohamed Al-Marhoon, Mohammad Ali Sadighi Gilani, Naif Alhathal, Nguyen Quang, Germar Michael Pinggera, Priyank Kothari, Sava Micic, Sheryl Homa, Tran Quang Tien Long, Wael Zohdy, Widi Atmoko, Wael Ibrahim, Marjan Sabbaghian, Saad Mohammed Abumelha, Eric Chung, Muhammet Rasit Ugur, Mehmet Serkan Ozkent, Osama Selim, Mahsa Darbandi, Shinichiro Fukuhara, Mounir Jamali, Jean de la Rosette, Shinnosuke Kuroda, Ryan P. Smith, Aykut Baser, Arif Kalkanli, Nicholas N. Tadros, Kaan Aydos, Tiago Cesar Mierzwa, Kareim Khalafalla, Vineet Malhotra, Mohamad Moussa, Federica Finocchi, Rinaldo Indra Rachman, Carlo Giulioni, Tomer Avidor-Reiss, Oguzhan Kahraman, Gökhan Çeker, Cătălina Zenoaga-Barbăroșie, Trenton L. Barrett, Mehmet Yilmaz, Ates Kadioglu, Sunil Jindal, Huda Omran, Kadir Bocu, Vilvapathy Senguttuvan Karthikeyan, Giorgio Franco, Jesús Fernando Solorzano, Ranjit B. Vishwakarma, Eko Arianto, Nicolas Garrido, Divyanu Jain, Nazim Gherabi, Ioannis Sokolakis, Ayad Palani, Gokhan Calik, Deniz Kulaksiz, Vaida Simanaviciene, Mara Simopoulou, Nur Dokuzeylül Güngör, Gideon Blecher, Marco Falcone, Davor Jezek, Mirko Preto, Edouard Amar, Tan V. Le, Sun Tae Ahn, Andri Rezano, Keerti Singh, Lucia Rocco, Missy Savira, Osvaldo Rajmil, Sara Darbandi, Emrullah Sogutdelen, Luca Boeri, Guadalupe Hernández, Lukman Hakim, Yoshiharu Morimoto, Andrian Japari, Nikolaos Sofikitis, Baris Altay, Asli Metin Mahmutoglu, Manaf Al Hashimi, Imad Ziouziou, Christina Anagnostopoulou, Haocheng Lin, Rupin Shah

Urology

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	202-215
Number of pages	14
Journal	World Journal of Men's Health
Volume	42
Issue number	1
DOIs	https://doi.org/10.5534/wjmh.230076
State	Published - Jan 2024

ASJC Scopus Subject Areas

Aging
Reproductive Medicine
Health Policy
Public Health, Environmental and Occupational Health
Psychiatry and Mental health
Urology
Pharmacology (medical)

Keywords

DNA fragmentation
Delphi method
Diagnostic test
Infertility
Survey
male

Access to Document

10.5534/wjmh.230076

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Agarwal, A., Farkouh, A., Saleh, R., Hamoda, T. A. A. A. M., Salvio, G., Boitrelle, F., Harraz, A. M., Ghayda, R. A., Kavoussi, P., Gül, M., Toprak, T., Russo, G. I., Durairajanayagam, D., Rambhatla, A., Birowo, P., Cannarella, R., Phuoc, N. H. V., Zini, A., Arafa, M., ... Shah, R. (2024). Technical Aspects and Clinical Limitations of Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations. World Journal of Men's Health, 42(1), 202-215. https://doi.org/10.5534/wjmh.230076

Agarwal, A, Farkouh, A, Saleh, R, Hamoda, TAAAM, Salvio, G, Boitrelle, F, Harraz, AM, Ghayda, RA, Kavoussi, P, Gül, M, Toprak, T, Russo, GI, Durairajanayagam, D, Rambhatla, A, Birowo, P, Cannarella, R, Phuoc, NHV, Zini, A, Arafa, M, Wyns, C, Tremellen, K, Sarıkaya, S, Lewis, S, Evenson, DP, Ko, E, Calogero, AE, Bahar, F, Martínez, M, Ambar, RF, Colpi, GM, Bakircioglu, ME, Henkel, R, Kandil, H, Serefoglu, EC, Alfakhri, A, Tsujimura, A, Kheradmand, A, Marino, A, Adamyan, A, Zilaitiene, B, Ozer, C, Pescatori, E, Vogiatzi, P, Busetto, GM, Balercia, G, Elbardisi, H, Akhavizadegan, H, Sajadi, H, Taniguchi, H, Park, HJ, Rosas, IM, Al-Marhoon, M, Gilani, MAS, Alhathal, N, Quang, N, Pinggera, GM, Kothari, P, Micic, S, Homa, S, Long, TQT, Zohdy, W, Atmoko, W, Ibrahim, W, Sabbaghian, M, Abumelha, SM, Chung, E, Ugur, MR, Ozkent, MS, Selim, O, Darbandi, M, Fukuhara, S, Jamali, M, de la Rosette, J, Kuroda, S, Smith, RP, Baser, A, Kalkanli, A, Tadros, NN, Aydos, K, Mierzwa, TC, Khalafalla, K, Malhotra, V, Moussa, M, Finocchi, F, Rachman, RI, Giulioni, C, Avidor-Reiss, T, Kahraman, O, Çeker, G, Zenoaga-Barbăroșie, C, Barrett, TL, Yilmaz, M, Kadioglu, A, Jindal, S, Omran, H, Bocu, K, Karthikeyan, VS, Franco, G, Solorzano, JF, Vishwakarma, RB, Arianto, E, Garrido, N, Jain, D, Gherabi, N, Sokolakis, I, Palani, A, Calik, G, Kulaksiz, D, Simanaviciene, V, Simopoulou, M, Güngör, ND, Blecher, G, Falcone, M, Jezek, D, Preto, M, Amar, E, Le, TV, Ahn, ST, Rezano, A, Singh, K, Rocco, L, Savira, M, Rajmil, O, Darbandi, S, Sogutdelen, E, Boeri, L, Hernández, G, Hakim, L, Morimoto, Y, Japari, A, Sofikitis, N, Altay, B, Mahmutoglu, AM, Al Hashimi, M, Ziouziou, I, Anagnostopoulou, C, Lin, H & Shah, R 2024, 'Technical Aspects and Clinical Limitations of Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations', World Journal of Men's Health, vol. 42, no. 1, pp. 202-215. https://doi.org/10.5534/wjmh.230076

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note = "Copyright {\textcopyright} 2024 Korean Society for Sexual Medicine and Andrology.",

year = "2024",

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doi = "10.5534/wjmh.230076",

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volume = "42",

pages = "202--215",

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AU - Saleh, Ramadan

AU - Hamoda, Taha Abo Almagd Abdel Meguid

AU - Salvio, Gianmaria

AU - Boitrelle, Florence

AU - Harraz, Ahmed M.

AU - Ghayda, Ramy Abou

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AU - Toprak, Tuncay

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AU - Rambhatla, Amarnath

AU - Birowo, Ponco

AU - Cannarella, Rossella

AU - Phuoc, Nguyen Ho Vinh

AU - Zini, Armand

AU - Arafa, Mohamed

AU - Wyns, Christine

AU - Tremellen, Kelton

AU - Sarıkaya, Selçuk

AU - Lewis, Sheena

AU - Evenson, Donald P.

AU - Ko, Edmund

AU - Calogero, Aldo E.

AU - Bahar, Fahmi

AU - Martínez, Marlon

AU - Ambar, Rafael F.

AU - Colpi, Giovanni M.

AU - Bakircioglu, Mustafa Emre

AU - Henkel, Ralf

AU - Kandil, Hussein

AU - Serefoglu, Ege Can

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AU - Marino, Angelo

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AU - Zilaitiene, Birute

AU - Ozer, Cevahir

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AU - Vogiatzi, Paraskevi

AU - Busetto, Gian Maria

AU - Balercia, Giancarlo

AU - Elbardisi, Haitham

AU - Akhavizadegan, Hamed

AU - Sajadi, Hesamoddin

AU - Taniguchi, Hisanori

AU - Park, Hyun Jun

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AU - Kahraman, Oguzhan

AU - Çeker, Gökhan

AU - Zenoaga-Barbăroșie, Cătălina

AU - Barrett, Trenton L.

AU - Yilmaz, Mehmet

AU - Kadioglu, Ates

AU - Jindal, Sunil

AU - Omran, Huda

AU - Bocu, Kadir

AU - Karthikeyan, Vilvapathy Senguttuvan

AU - Franco, Giorgio

AU - Solorzano, Jesús Fernando

AU - Vishwakarma, Ranjit B.

AU - Arianto, Eko

AU - Garrido, Nicolas

AU - Jain, Divyanu

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AU - Palani, Ayad

AU - Calik, Gokhan

AU - Kulaksiz, Deniz

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AU - Falcone, Marco

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AU - Preto, Mirko

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AU - Le, Tan V.

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AU - Singh, Keerti

AU - Rocco, Lucia

AU - Savira, Missy

AU - Rajmil, Osvaldo

AU - Darbandi, Sara

AU - Sogutdelen, Emrullah

AU - Boeri, Luca

AU - Hernández, Guadalupe

AU - Hakim, Lukman

AU - Morimoto, Yoshiharu

AU - Japari, Andrian

AU - Sofikitis, Nikolaos

AU - Altay, Baris

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KW - Diagnostic test

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Technical Aspects and Clinical Limitations of Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations

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Keywords

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