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Targeting C/EBP homologous protein with siRNA attenuates cerebral vasospasm after experimental subarachnoid hemorrhage

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)218-224
Number of pages7
JournalExperimental Neurology
Volume238
Issue number2
DOIs
StatePublished - Dec 2012

ASJC Scopus Subject Areas

  • Neurology
  • Developmental Neuroscience

Keywords

  • Apoptosis
  • Bcl-2
  • Bim
  • C/EBP homologous protein
  • Caspase-3
  • Cerebral vasospasm
  • SiRNA
  • Subarachnoid hemorrhage
  • Caspase 3/metabolism
  • Endothelial Cells/drug effects
  • Cell Count
  • Male
  • Transcription Factor CHOP/genetics
  • Subarachnoid Hemorrhage/complications
  • Bcl-2-Like Protein 11
  • Apoptosis Regulatory Proteins/metabolism
  • Disease Models, Animal
  • In Situ Nick-End Labeling
  • Proto-Oncogene Proteins/metabolism
  • Rats
  • Endothelium/drug effects
  • Rats, Sprague-Dawley
  • Animals
  • Analysis of Variance
  • Basilar Artery/pathology
  • Membrane Proteins/metabolism
  • von Willebrand Factor/metabolism
  • Proto-Oncogene Proteins c-bcl-2/metabolism
  • Vasospasm, Intracranial/etiology
  • RNA, Small Interfering/therapeutic use

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