TY - JOUR
T1 - Systematized contact dermatitis and montelukast in an atopic boy
AU - Castanedo-Tardan, Mari Paz
AU - González, Mercedes E.
AU - Connelly, Elizabeth A.
AU - Giordano, Kelly
AU - Jacob, Sharon E.
N1 - Pediatr Dermatol. 2009 Nov-Dec;26(6):739-43. doi: 10.1111/j.1525-1470.2008.00855.x. Case Reports
PY - 2009
Y1 - 2009
N2 - Upon ingestion, the artificial sweetener, aspartame is metabolized to formaldehyde in the body and has been reportedly associated with systemic contact dermatitis in patients exquisitely sensitive to formaldehyde. We present a case of a 9-year-old Caucasian boy with a history of mild atopic dermatitis that experienced severe systematized dermatitis after being started on montelukast chewable tablets containing aspartame. Patch testing revealed multiple chemical sensitivities which included a positive reaction to formaldehyde. Notably, resolution of his systemic dermatitis only occurred with discontinuation of the montelukast chewables.
AB - Upon ingestion, the artificial sweetener, aspartame is metabolized to formaldehyde in the body and has been reportedly associated with systemic contact dermatitis in patients exquisitely sensitive to formaldehyde. We present a case of a 9-year-old Caucasian boy with a history of mild atopic dermatitis that experienced severe systematized dermatitis after being started on montelukast chewable tablets containing aspartame. Patch testing revealed multiple chemical sensitivities which included a positive reaction to formaldehyde. Notably, resolution of his systemic dermatitis only occurred with discontinuation of the montelukast chewables.
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U2 - 10.1111/j.1525-1470.2008.00855.x
DO - 10.1111/j.1525-1470.2008.00855.x
M3 - Article
C2 - 20199453
SN - 0736-8046
VL - 26
SP - 739
EP - 743
JO - Pediatric Dermatology
JF - Pediatric Dermatology
IS - 6
ER -