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SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS

  • Gabriel R. Linares
  • , Yichen Li
  • , Wen Hsuan Chang
  • , Jasper Rubin-Sigler
  • , Stacee Mendonca
  • , Sarah Hong
  • , Yunsun Eoh
  • , Wenxuan Guo
  • , Yi Hsuan Huang
  • , Jonathan Chang
  • , Sharon Tu
  • , Nomongo Dorjsuren
  • , Manuel Santana
  • , Shu Ting Hung
  • , Johnny Yu
  • , Joscany Perez
  • , Michael Chickering
  • , Tze Yuan Cheng
  • , Chi Chou Huang
  • , Shih Jong James Lee
  • Hao Jen Deng, Kieu Tram Bach, Kamden Gray, Vishvak Subramanyam, Jeffrey Rosenfeld, Samuel V. Alworth, Hani Goodarzi, Justin K. Ichida

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)171-187.e14
JournalCell Stem Cell
Volume30
Issue number2
DOIs
StatePublished - Feb 2 2023

ASJC Scopus Subject Areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

Keywords

  • SYF2
  • TDP-43
  • amyotrophic lateral sclerosis
  • androgens
  • connectivity map
  • drug screen
  • induced pluripotent stem cells
  • nineteen complex
  • norgestrel
  • spliceosome

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