SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS

Gabriel R. Linares; Yichen Li; Wen Hsuan Chang; Jasper Rubin-Sigler; Stacee Mendonca; Sarah Hong; Yunsun Eoh; Wenxuan Guo; Yi Hsuan Huang; Jonathan Chang; Sharon Tu; Nomongo Dorjsuren; Manuel Santana; Shu Ting Hung; Johnny Yu; Joscany Perez; Michael Chickering; Tze Yuan Cheng; Chi Chou Huang; Shih Jong James Lee; Hao Jen Deng; Kieu Tram Bach; Kamden Gray; Vishvak Subramanyam; Jeffrey Rosenfeld; Samuel V. Alworth; Hani Goodarzi; Justin K. Ichida

doi:10.1016/j.stem.2023.01.005

SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS

Gabriel R. Linares, Yichen Li, Wen Hsuan Chang, Jasper Rubin-Sigler, Stacee Mendonca, Sarah Hong, Yunsun Eoh, Wenxuan Guo, Yi Hsuan Huang, Jonathan Chang, Sharon Tu, Nomongo Dorjsuren, Manuel Santana, Shu Ting Hung, Johnny Yu, Joscany Perez, Michael Chickering, Tze Yuan Cheng, Chi Chou Huang, Shih Jong James LeeHao Jen Deng, Kieu Tram Bach, Kamden Gray, Vishvak Subramanyam, Jeffrey Rosenfeld, Samuel V. Alworth, Hani Goodarzi, Justin K. Ichida

Neurology

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	171-187.e14
Journal	Cell Stem Cell
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/j.stem.2023.01.005
State	Published - Feb 2 2023

ASJC Scopus Subject Areas

Molecular Medicine
Genetics
Cell Biology

Keywords

SYF2
TDP-43
amyotrophic lateral sclerosis
androgens
connectivity map
drug screen
induced pluripotent stem cells
nineteen complex
norgestrel
spliceosome

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Linares, G. R., Li, Y., Chang, W. H., Rubin-Sigler, J., Mendonca, S., Hong, S., Eoh, Y., Guo, W., Huang, Y. H., Chang, J., Tu, S., Dorjsuren, N., Santana, M., Hung, S. T., Yu, J., Perez, J., Chickering, M., Cheng, T. Y., Huang, C. C., ... Ichida, J. K. (2023). SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS. Cell Stem Cell, 30(2), 171-187.e14. https://doi.org/10.1016/j.stem.2023.01.005

Linares, GR, Li, Y, Chang, WH, Rubin-Sigler, J, Mendonca, S, Hong, S, Eoh, Y, Guo, W, Huang, YH, Chang, J, Tu, S, Dorjsuren, N, Santana, M, Hung, ST, Yu, J, Perez, J, Chickering, M, Cheng, TY, Huang, CC, Lee, SJJ, Deng, HJ, Bach, KT, Gray, K, Subramanyam, V, Rosenfeld, J, Alworth, SV, Goodarzi, H & Ichida, JK 2023, 'SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS', Cell Stem Cell, vol. 30, no. 2, pp. 171-187.e14. https://doi.org/10.1016/j.stem.2023.01.005

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AU - Gray, Kamden

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SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS

ASJC Scopus Subject Areas

Keywords

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