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Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme

  • Zhang Ping
  • , Wenwu Liu
  • , Zhimin Kang
  • , Jianmei Cai
  • , Qiusha Wang
  • , Ni Cheng
  • , Sujian Wang
  • , Shizhong Wang
  • , John H. Zhang
  • , Xuejun Sun

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)178-185
Number of pages8
JournalBrain Research
Volume1343
DOIs
StatePublished - Jul 9 2010

ASJC Scopus Subject Areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Keywords

  • Heme oxygenase 1
  • Hypoxic ischemia
  • NF-E2-related factor-2
  • ROS
  • Sulforaphane
  • Animals, Newborn
  • Apoptosis/drug effects
  • Rats
  • Sulfoxides
  • Biomarkers/metabolism
  • Neuroprotective Agents/pharmacology
  • Rats, Sprague-Dawley
  • Hypoxia-Ischemia, Brain/drug therapy
  • Animals
  • NAD(P)H Dehydrogenase (Quinone)/biosynthesis
  • Second Messenger Systems/drug effects
  • Heme Oxygenase (Decyclizing)/physiology
  • Enzyme Induction/drug effects
  • NF-E2-Related Factor 2/physiology
  • Isothiocyanates
  • Thiocyanates/pharmacology
  • Nerve Degeneration/drug therapy
  • Disease Models, Animal

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