Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled Bile acid receptor 1 (GP-BAR1, TGR5) agonists

Donna D. Yu; Kyle M. Sousa; Daniell L. Mattern; Jeffrey Wagner; Xianghui Fu; Nagarajan Vaidehi; Barry M. Forman; Wendong Huang

doi:10.1016/j.bmc.2015.01.048

Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled Bile acid receptor 1 (GP-BAR1, TGR5) agonists

Donna D. Yu, Kyle M. Sousa, Daniell L. Mattern, Jeffrey Wagner, Xianghui Fu, Nagarajan Vaidehi, Barry M. Forman, Wendong Huang

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1613-1628
Number of pages	16
Journal	Bioorganic and Medicinal Chemistry
Volume	23
Issue number	7
DOIs	https://doi.org/10.1016/j.bmc.2015.01.048
State	Published - Apr 1 2015
Externally published	Yes

ASJC Scopus Subject Areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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title = "Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled Bile acid receptor 1 (GP-BAR1, TGR5) agonists",

author = "Yu, {Donna D.} and Sousa, {Kyle M.} and Mattern, {Daniell L.} and Jeffrey Wagner and Xianghui Fu and Nagarajan Vaidehi and Forman, {Barry M.} and Wendong Huang",

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AU - Wagner, Jeffrey

AU - Fu, Xianghui

AU - Vaidehi, Nagarajan

AU - Forman, Barry M.

AU - Huang, Wendong

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JO - Bioorganic and Medicinal Chemistry

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Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled Bile acid receptor 1 (GP-BAR1, TGR5) agonists

ASJC Scopus Subject Areas

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