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Stem cell antigen-1 positive cell-based systemic human growth hormone gene transfer strategy increases endosteal bone resorption and bone loss in mice

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)77-88
Number of pages12
JournalJournal of Gene Medicine
Volume13
Issue number2
DOIs
StatePublished - Feb 2011

ASJC Scopus Subject Areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Drug Discovery
  • Genetics(clinical)

Keywords

  • Bone resorption
  • Gene therapy
  • Growth hormone
  • IGF-I
  • Marrow transplantation
  • Sca-1
  • Stem cell
  • Bone Resorption/diagnostic imaging
  • Whole-Body Irradiation
  • Humans
  • Membrane Proteins/genetics
  • Male
  • Bone and Bones/anatomy & histology
  • Bone Marrow Transplantation
  • HEK293 Cells
  • Femur/anatomy & histology
  • Bone Marrow Cells/metabolism
  • Gene Transfer Techniques
  • Transduction, Genetic
  • Antigens, Ly/genetics
  • Mice, Inbred C57BL
  • Gene Expression Regulation
  • Mice, Transgenic
  • Gene Dosage
  • RNA, Messenger/metabolism
  • Radiography
  • Animals
  • Genetic Vectors/genetics
  • Mice
  • Human Growth Hormone/genetics
  • Lentivirus/genetics

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