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SPARC coordinates extracellular matrix remodeling and efficient recruitment to and migration of antigen-specific T cells in the brain following infection

  • Kathryn E. McGovern
  • , J. Philip Nance
  • , Clément N. David
  • , Reed E.S. Harrison
  • , Shahani Noor
  • , Danielle Worth
  • , Tyler A. Landrith
  • , Andre Obenaus
  • , Monica J. Carson
  • , Dimitrios Morikis
  • , Emma H. Wilson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number4549
JournalScientific Reports
Volume11
Issue number1
DOIs
StatePublished - Feb 25 2021
Externally publishedYes

ASJC Scopus Subject Areas

  • General

Keywords

  • Extracellular Matrix/metabolism
  • Osteonectin/genetics
  • T-Lymphocytes/immunology
  • Receptors, CCR7
  • Gene Expression Regulation
  • Toxoplasmosis, Cerebral/etiology
  • Antigens, Protozoan/immunology
  • Host-Parasite Interactions/immunology
  • Brain/blood supply
  • Mice, Knockout
  • Cell Movement/immunology
  • Animals
  • Neurons/metabolism
  • Chemokine CCL21/metabolism
  • Biomarkers
  • Protein Binding
  • Epitopes, T-Lymphocyte/immunology
  • Mice
  • Toxoplasma/physiology
  • Disease Models, Animal

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