TY - JOUR
T1 - Slow variation of the amplitude of acoustic distortion at f2-f1 in awake rabbits
AU - Whitehead, M. L.
AU - Lonsbury-Martin, B. L.
AU - Martin, G. K.
N1 - Funding Information:
This research was supported in part by funds from the Public Health Service (DC00313, DC 00613, ES03500) and the Deafness Research Foundation to Baylor College of Medicine. The authors thank B.B. Stagner, D.J. Murray and D.L. Himes for technical assistance.
PY - 1991/2
Y1 - 1991/2
N2 - A slow, reversible change in f2-f1 distortion-product otoacoustic emission (DPOAE) amplitude in the absence of correlated changes in 2f1-f2 DPOAE amplitude has been recently reported in anesthetized guinea pigs and gerbils, suggesting a dissociation in the generation of these two emissions. It was proposed that the observed changes in f2-f1 amplitude may represent an efferent influence on cochlear mechanics [Brown A.M., Hear. Res., 34, 27-38, 1988]. In the present study, a search was made for similar changes in f2-f1amplitude in awake rabbits. Qualitatively similar variations in f2-f1 DPOAE amplitude, in the absence of 2f1-f2 amplitude variations, were found in all ears tested, supporting the hypothesis of a dissociation of the generators of the two DPOAEs. The behavior of the f2-f1 DPOAE amplitude changes observed here, however, provided no evidence of an efferent involvement.
AB - A slow, reversible change in f2-f1 distortion-product otoacoustic emission (DPOAE) amplitude in the absence of correlated changes in 2f1-f2 DPOAE amplitude has been recently reported in anesthetized guinea pigs and gerbils, suggesting a dissociation in the generation of these two emissions. It was proposed that the observed changes in f2-f1 amplitude may represent an efferent influence on cochlear mechanics [Brown A.M., Hear. Res., 34, 27-38, 1988]. In the present study, a search was made for similar changes in f2-f1amplitude in awake rabbits. Qualitatively similar variations in f2-f1 DPOAE amplitude, in the absence of 2f1-f2 amplitude variations, were found in all ears tested, supporting the hypothesis of a dissociation of the generators of the two DPOAEs. The behavior of the f2-f1 DPOAE amplitude changes observed here, however, provided no evidence of an efferent involvement.
KW - Distortion-product otoacoustic emissions
KW - Olivocochlear efferents
KW - Rabbit
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U2 - 10.1016/0378-5955(91)90045-B
DO - 10.1016/0378-5955(91)90045-B
M3 - Article
C2 - 2032963
SN - 0378-5955
VL - 51
SP - 293
EP - 300
JO - Hearing Research
JF - Hearing Research
IS - 2
ER -