Slow-twitch oxidative myofiber proportions and capillary number per myofiber are reduced in growth-restricted fetal sheep

Tristan B. Dear; Eileen I. Chang; Saif I. Al-Juboori; Jane Stremming; Stephanie R. Wesolowski; Sonnet S. Jonker; Paul J. Rozance; Evgenia Dobrinskikh; Laura D. Brown

doi:10.1152/ajpregu.00044.2025

Slow-twitch oxidative myofiber proportions and capillary number per myofiber are reduced in growth-restricted fetal sheep

Tristan B. Dear
, Eileen I. Chang
, Saif I. Al-Juboori
, Jane Stremming
, Stephanie R. Wesolowski
, Sonnet S. Jonker
, Paul J. Rozance
, Evgenia Dobrinskikh
, Laura D. Brown

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	R907-R919
Journal	American journal of physiology. Regulatory, integrative and comparative physiology
Volume	329
Issue number	6
DOIs	https://doi.org/10.1152/ajpregu.00044.2025
State	Published - Dec 1 2025
Externally published	Yes

ASJC Scopus Subject Areas

Physiology
Physiology (medical)

Keywords

fast-twitch myofibers
fetal growth
oxidative myofibers
skeletal muscle development
vascularity
Capillaries/pathology
Muscle, Skeletal/blood supply
Gestational Age
Muscle Fibers, Slow-Twitch/pathology
Pregnancy
Animals
Fetal Growth Retardation/physiopathology
Placental Insufficiency/physiopathology
Female
Sheep
Disease Models, Animal

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10.1152/ajpregu.00044.2025

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Dear, T. B., Chang, E. I., Al-Juboori, S. I., Stremming, J., Wesolowski, S. R., Jonker, S. S., Rozance, P. J., Dobrinskikh, E., & Brown, L. D. (2025). Slow-twitch oxidative myofiber proportions and capillary number per myofiber are reduced in growth-restricted fetal sheep. American journal of physiology. Regulatory, integrative and comparative physiology, 329(6), R907-R919. https://doi.org/10.1152/ajpregu.00044.2025

Slow-twitch oxidative myofiber proportions and capillary number per myofiber are reduced in growth-restricted fetal sheep. / Dear, Tristan B.; Chang, Eileen I.; Al-Juboori, Saif I. et al.
In: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 329, No. 6, 01.12.2025, p. R907-R919.

Research output: Contribution to journal › Article › peer-review

Dear, TB, Chang, EI, Al-Juboori, SI, Stremming, J, Wesolowski, SR, Jonker, SS, Rozance, PJ, Dobrinskikh, E & Brown, LD 2025, 'Slow-twitch oxidative myofiber proportions and capillary number per myofiber are reduced in growth-restricted fetal sheep', American journal of physiology. Regulatory, integrative and comparative physiology, vol. 329, no. 6, pp. R907-R919. https://doi.org/10.1152/ajpregu.00044.2025

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AU - Stremming, Jane

AU - Wesolowski, Stephanie R.

AU - Jonker, Sonnet S.

AU - Rozance, Paul J.

AU - Dobrinskikh, Evgenia

AU - Brown, Laura D.

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KW - Disease Models, Animal

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Slow-twitch oxidative myofiber proportions and capillary number per myofiber are reduced in growth-restricted fetal sheep

ASJC Scopus Subject Areas

Keywords

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