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Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme

  • Szu Ting Chou
  • , Rameshwar Patil
  • , Anna Galstyan
  • , Pallavi R. Gangalum
  • , Webster K. Cavenee
  • , Frank B. Furnari
  • , Vladimir A. Ljubimov
  • , Alexandra Chesnokova
  • , Andrei A. Kramerov
  • , Hui Ding
  • , Vida Falahatian
  • , Leila Mashouf
  • , Irving Fox
  • , Keith L. Black
  • , Eggehard Holler
  • , Alexander V. Ljubimov
  • , Julia Y. Ljubimova

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)14-23
Number of pages10
JournalJournal of Controlled Release
Volume244
DOIs
StatePublished - Dec 28 2016
Externally publishedYes

ASJC Scopus Subject Areas

  • Pharmaceutical Science

Keywords

  • Blood-brain barrier delivery
  • Dual antisense oligonucleotide-dual antibody nanobioconjugate
  • EGFR/EGFRvIII
  • Glioblastoma multiforme
  • Protein kinase CK2

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