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Sertoli cells improve survival of motor neurons in SOD1 transgenic mice, a model of amyotrophic lateral sclerosis

  • Richelle Hemendinger
  • , Jay Wang
  • , Saafan Malik
  • , Rafal Persinski
  • , Jane Copeland
  • , Dwaine Emerich
  • , Paul Gores
  • , Craig Halberstadt
  • , Jeffrey Rosenfeld

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)235-243
Number of pages9
JournalExperimental Neurology
Volume196
Issue number2
DOIs
StatePublished - Dec 2005
Externally publishedYes

Keywords

  • Amyotrophic Lateral Sclerosis/surgery
  • Animals
  • Blotting, Western/methods
  • Cell Count
  • Cell Survival/physiology
  • Cells, Cultured
  • Choline O-Acetyltransferase/metabolism
  • DNA/analysis
  • Disease Models, Animal
  • Female
  • Functional Laterality
  • GATA4 Transcription Factor/metabolism
  • Gene Expression Regulation/physiology
  • Humans
  • Immunohistochemistry/methods
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Motor Neurons/physiology
  • Nerve Growth Factors/metabolism
  • Sertoli Cells/physiology
  • Spinal Cord/cytology
  • Superoxide Dismutase/genetics

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