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Role of oxidative stress in high-glucose- and diabetes-induced increased expression of Gq/11α proteins and associated signaling in vascular smooth muscle cells

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)1395-1405
Number of pages11
JournalFree Radical Biology and Medicine
Volume49
Issue number9
DOIs
StatePublished - Nov 15 2010
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Physiology (medical)

Keywords

  • Free radicals
  • Gqα protein
  • High glucose
  • Oxidative stress
  • PI turnover
  • PLCβ
  • VSMC
  • Endothelium, Vascular/pathology
  • Superoxide Dismutase/genetics
  • Oxidative Stress
  • Hydrogen Peroxide/metabolism
  • Male
  • Diabetes Mellitus, Type 1/chemically induced
  • Streptozocin/administration & dosage
  • GTP-Binding Protein alpha Subunits, Gq-G11/genetics
  • Cell Line
  • Antioxidants/pharmacology
  • Signal Transduction
  • Gene Expression Regulation
  • Rats
  • Myocytes, Smooth Muscle/drug effects
  • Rats, Sprague-Dawley
  • Animals
  • Glucose/administration & dosage
  • Phospholipase C beta/genetics
  • Superoxide Dismutase-1

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