Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury

Ikuyo Kusaka, Gen Kusaka, Changman Zhou, Mami Ishikawa, Anil Nanda, D. Neil Granger, John H. Zhang, Jiping Tang

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)H2442-H2451
JournalAmerican Journal of Physiology - Heart and Circulatory Physiology
Volume286
Issue number6
DOIs
StatePublished - Jun 2004
Externally publishedYes

ASJC Scopus Subject Areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Keywords

  • Angiotensin type 1 receptor antagonist
  • Blood Pressure
  • Immunohistochemistry
  • Membrane Glycoproteins/genetics
  • Receptor, Angiotensin, Type 1/metabolism
  • Body Weight
  • Male
  • Brain Edema/drug therapy
  • Brain Infarction/drug therapy
  • NADPH Oxidases/genetics
  • Antihypertensive Agents/pharmacology
  • Diabetic Angiopathies/drug therapy
  • Disease Models, Animal
  • Brain Ischemia/drug therapy
  • Tetrazoles/pharmacology
  • Carbon Dioxide/blood
  • Rats
  • Blood Glucose
  • Biphenyl Compounds
  • NADPH Oxidase 2
  • Rats, Sprague-Dawley
  • Membrane Transport Proteins/genetics
  • Phosphoproteins/genetics
  • Animals
  • Benzimidazoles/pharmacology
  • RNA, Messenger/analysis
  • NADPH Dehydrogenase/genetics
  • Lipid Peroxidation
  • Oxygen/blood

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