TY - JOUR
T1 - Rnai-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis b virus DNA is a source of hbsag
AU - Wooddell, Christine I.
AU - Yuen, Man Fung
AU - Chan, Henry Lik Yuen
AU - Gish, Robert G.
AU - Locarnini, Stephen A.
AU - Chavez, Deborah
AU - Ferrari, Carl
AU - Given, Bruce D.
AU - Hamilton, James
AU - Kanner, Steven B.
AU - Lai, Ching Lung
AU - Lau, Johnson Y.N.
AU - Schluep, Thomas
AU - Xu, Zhao
AU - Lanford, Robert E.
AU - Lewis, David L.
N1 - Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
PY - 2017/9/27
Y1 - 2017/9/27
KW - Hepatitis B e Antigens/metabolism
KW - Humans
KW - Virus Replication/drug effects
KW - Hepatitis B, Chronic/pathology
KW - Pan troglodytes
KW - Polyadenylation/drug effects
KW - RNA, Messenger/genetics
KW - RNA, Viral/metabolism
KW - Hepatitis B Surface Antigens/metabolism
KW - Liver/pathology
KW - RNA, Small Interfering/metabolism
KW - Animals
KW - DNA, Viral/metabolism
KW - Base Sequence
KW - RNA Interference/drug effects
KW - Antiviral Agents/pharmacology
KW - Hepatitis B virus/drug effects
KW - Virus Integration/drug effects
UR - https://www.scopus.com/pages/publications/85030237448
UR - https://www.scopus.com/pages/publications/85030237448#tab=citedBy
UR - https://www.mendeley.com/catalogue/c8bd5fc8-1339-3c85-b8a6-f48b5980cc88/
U2 - 10.1126/scitranslmed.aan0241
DO - 10.1126/scitranslmed.aan0241
M3 - Article
C2 - 28954926
AN - SCOPUS:85030237448
SN - 1946-6234
VL - 9
JO - Science Translational Medicine
JF - Science Translational Medicine
IS - 409
M1 - eaan0241
ER -