Ribosomal DNA Assay of Culture-Negative Streptococcus pneumoniae Meningitis

Donald L. Janner; Will S. Probert; Chalmer D. McClure

doi:10.1016/j.pediatrneurol.2007.03.007

Ribosomal DNA Assay of Culture-Negative Streptococcus pneumoniae Meningitis

Donald L. Janner, Will S. Probert, Chalmer D. McClure

Pediatric Neurology Division

Research output: Contribution to journal › Article › peer-review

Abstract

Culture-negative bacterial meningitis with secondary complications remains a significant challenge. Optimal treatment requires identification of the infecting organism. While the gold standard for diagnosis remains cerebrospinal fluid culturing, a significant number of cultures remain negative despite clinical evidence of meningitis. This patient illustrates the usefulness of polymerase chain reaction technology in identifying a specific organism, in an otherwise culture-negative bacterial meningitis with spinal cord abscess.

Original language	English
Pages (from-to)	55-58
Number of pages	4
Journal	Pediatric Neurology
Volume	37
Issue number	1
DOIs	https://doi.org/10.1016/j.pediatrneurol.2007.03.007
State	Published - Jul 2007

ASJC Scopus Subject Areas

Pediatrics, Perinatology, and Child Health
Neurology
Developmental Neuroscience
Clinical Neurology

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title = "Ribosomal DNA Assay of Culture-Negative Streptococcus pneumoniae Meningitis",

abstract = "Culture-negative bacterial meningitis with secondary complications remains a significant challenge. Optimal treatment requires identification of the infecting organism. While the gold standard for diagnosis remains cerebrospinal fluid culturing, a significant number of cultures remain negative despite clinical evidence of meningitis. This patient illustrates the usefulness of polymerase chain reaction technology in identifying a specific organism, in an otherwise culture-negative bacterial meningitis with spinal cord abscess.",

author = "Janner, {Donald L.} and Probert, {Will S.} and McClure, {Chalmer D.}",

note = "Funding Information: We wish to acknowledge the support of the California Encephalitis Project of the California Department of Health Services in performing the 16S ribosomal DNA assay.",

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Ribosomal DNA Assay of Culture-Negative Streptococcus pneumoniae Meningitis

Abstract

ASJC Scopus Subject Areas

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