Reversal of hyperglycemia and suppression of type 1 diabetes in the NOD mouse with apoptotic DNA immunotherapy (ADi), ADi-100

David G. Alleva, Melika Rezaee, Linda Yip, Gang Ren, Jarrett Rosenberg, Waldo Concepcion, Alan Escher, Shahrokh Shabahang, Avnesh S. Thakor

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number53
JournalBiomedicines
Volume8
Issue number3
DOIs
StatePublished - Mar 1 2020
Externally publishedYes

ASJC Scopus Subject Areas

  • Medicine (miscellaneous)
  • General Biochemistry,Genetics and Molecular Biology

Keywords

  • ADi-100
  • Antigen-specific
  • Apoptosis
  • BAX
  • DNA immunotherapy
  • DNA plasmids
  • Diabetes
  • Hyperglycemia
  • Immunotherapy
  • Monotherapy
  • NOD mouse
  • Pre-diabetic mouse
  • T cells
  • Type 1 diabetes
  • sGAD55

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