TY - JOUR
T1 - Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes
AU - Goulopoulou, Styliani
AU - Hannan, Johanna L.
AU - Matsumoto, Takayuki
AU - Ogbi, Safia
AU - Ergul, Adviye
AU - Webb, R. Clinton
N1 - Copyright © 2015 the American Physiological Society.
PY - 2015/7/15
Y1 - 2015/7/15
KW - Sildenafil
KW - Soluble guanylyl cycle agonists
KW - Type 2 diabetes
KW - Vascular smooth muscle
KW - Vasorelaxation
KW - Guanylate Cyclase/metabolism
KW - Purines/pharmacology
KW - Arterial Pressure/drug effects
KW - Phosphodiesterase 5 Inhibitors/pharmacology
KW - Nitric Oxide/metabolism
KW - Vasodilation/drug effects
KW - Dose-Response Relationship, Drug
KW - Sildenafil Citrate
KW - Vasodilator Agents/pharmacology
KW - Cyclic GMP-Dependent Protein Kinases/metabolism
KW - Diabetic Angiopathies/drug therapy
KW - Female
KW - Disease Models, Animal
KW - Cyclic GMP/metabolism
KW - Enzyme Activators/pharmacology
KW - Piperazines/pharmacology
KW - Rats
KW - Soluble Guanylyl Cyclase
KW - Diabetes Mellitus, Type 2/complications
KW - Receptors, Cytoplasmic and Nuclear/agonists
KW - Animals
KW - Sulfonamides/pharmacology
KW - Mesenteric Arteries/drug effects
KW - Enzyme Activation
UR - https://www.scopus.com/pages/publications/84937417518
UR - https://www.scopus.com/pages/publications/84937417518#tab=citedBy
UR - https://www.mendeley.com/catalogue/e0dbf460-8b0e-3809-8b86-85ac7c714dfd/
U2 - 10.1152/ajpheart.00079.2015
DO - 10.1152/ajpheart.00079.2015
M3 - Article
C2 - 25957216
AN - SCOPUS:84937417518
SN - 0363-6135
VL - 309
SP - H297-H304
JO - American Journal of Physiology - Heart and Circulatory Physiology
JF - American Journal of Physiology - Heart and Circulatory Physiology
IS - 2
ER -