Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

C. E. Brown; L. Howe; K. Sousa; S. C. Alley; M. J. Carrozza; S. Tan; J. L. Workman

doi:10.1126/science.1060214

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

C. E. Brown, L. Howe, K. Sousa, S. C. Alley, M. J. Carrozza, S. Tan, J. L. Workman

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2333-2337
Number of pages	5
Journal	Science
Volume	292
Issue number	5525
DOIs	https://doi.org/10.1126/science.1060214
State	Published - Jun 22 2001
Externally published	Yes

ASJC Scopus Subject Areas

General

Access to Document

10.1126/science.1060214

OpenUrl availability

Full text

Cite this

@article{6130f3867b384c3692408dfbbf8c5fae,

title = "Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit",

author = "Brown, {C. E.} and L. Howe and K. Sousa and Alley, {S. C.} and Carrozza, {M. J.} and S. Tan and Workman, {J. L.}",

note = "Promoter-specific recruitment of histone acetyltransferase activity is often critical for transcriptional activation. We present a detailed study of the interaction between the histone acetyltransferase complexes SAGA and NuA4, and transcription activators. We demonstrate by affinity chromatography and photo-cross-linking label transfer that acidic activators directly interact with Tra1p, a shared subunit of SAGA and NuA4.",

year = "2001",

month = jun,

day = "22",

doi = "10.1126/science.1060214",

language = "English",

volume = "292",

pages = "2333--2337",

journal = "Science",

issn = "0036-8075",

number = "5525",

}

TY - JOUR

T1 - Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

AU - Brown, C. E.

AU - Howe, L.

AU - Sousa, K.

AU - Alley, S. C.

AU - Carrozza, M. J.

AU - Tan, S.

AU - Workman, J. L.

N1 - Promoter-specific recruitment of histone acetyltransferase activity is often critical for transcriptional activation. We present a detailed study of the interaction between the histone acetyltransferase complexes SAGA and NuA4, and transcription activators. We demonstrate by affinity chromatography and photo-cross-linking label transfer that acidic activators directly interact with Tra1p, a shared subunit of SAGA and NuA4.

PY - 2001/6/22

Y1 - 2001/6/22

UR - http://www.scopus.com/inward/record.url?scp=0035933521&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035933521&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/e9504d5a-e755-38c4-84b1-318f6565b255/

U2 - 10.1126/science.1060214

DO - 10.1126/science.1060214

M3 - Article

SN - 0036-8075

VL - 292

SP - 2333

EP - 2337

JO - Science

JF - Science

IS - 5525

ER -

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit

ASJC Scopus Subject Areas

Access to Document

OpenUrl availability

Other files and links

Cite this