TY - JOUR
T1 - Radionuclide Detection of Diffuse Interstitial Pulmonary Calcification
AU - Grames, George M.
AU - Sauser, Donald D.
AU - Jansen, Carl
AU - Soderblom, Robert E.
AU - Hodgkin, John E.
AU - Stilson, Mildred S.
N1 - JAMA. 1974 Nov 18;230(7):992-5.
PY - 1974/11/18
Y1 - 1974/11/18
N2 - Two patients who had hypercalcemia, one from multiple myeloma and the other from metastatic carcinoma, showed striking concentrations of bone-seeking radiopharmaceuticals in the lungs on routine bone scans. Neither patient had roentgenographic evidence of intrapulmonary calcification. Histologic examination in one patient showed extensive interstitial pulmonary calcification. These cases dramatically illustrate the capability of radionuclides to detect interstitial pulmonary calcification when radiographic demonstration is lacking. The early detection of extraskeletal calcification by bone-seeking radionuclides provides a unique opportunity, not previously available, to study metastatic calcification and the effects of treatment.
AB - Two patients who had hypercalcemia, one from multiple myeloma and the other from metastatic carcinoma, showed striking concentrations of bone-seeking radiopharmaceuticals in the lungs on routine bone scans. Neither patient had roentgenographic evidence of intrapulmonary calcification. Histologic examination in one patient showed extensive interstitial pulmonary calcification. These cases dramatically illustrate the capability of radionuclides to detect interstitial pulmonary calcification when radiographic demonstration is lacking. The early detection of extraskeletal calcification by bone-seeking radionuclides provides a unique opportunity, not previously available, to study metastatic calcification and the effects of treatment.
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U2 - 10.1001/jama.1974.03240070026020
DO - 10.1001/jama.1974.03240070026020
M3 - Article
C2 - 4479544
SN - 0098-7484
VL - 230
SP - 992
EP - 995
JO - JAMA
JF - JAMA
IS - 7
ER -