TY - JOUR
T1 - Psychosocial implications during adolescence for infant heart transplant recipients
AU - Krishnamurthy, Vidhya
AU - Randall, Catherin Freier
AU - Chinnock, Richard
N1 - Funding Information:
This research was funded by the ANPCyT SECyT PiCT 2004. grant Nº 25722 and Universidad Nacional del Comahue Grant Nº B001. Our sincere appreciations to A. Denegri for her work on figures and to the National Park rangers Tata and G.
PY - 2011/5
Y1 - 2011/5
N2 - Background & Objectives: As more heart transplant recipients survive into late adolescence, research addressing long-term psychosocial and neurodevelopmental outcomes is imperative. The limited literature available suggests risk for psychosocial difficulties and lower cognitive, academic, and neuropsychological functioning. This paper reviews topic-related literature and provides preliminary data examining psychosocial and neuropsychological functioning of adolescents who received their heart transplant during infancy. Method: This paper offers a literature review AND presents preliminary data from studies conducted through Loma Linda University Children's Hospital (LLUCH). Study one examined psychosocial functioning and quality of life of adolescent infant heart transplant recipients. In study two, cognitive, academic, and neuropsychological data were analyzed. Results: Study 1: Overall psychosocial functioning fell in the Average range, however, a significant percentage of participants presented with difficulties on one or more of the psychosocial domains. Quality of life was also within normal limits, though concerns with general health and bodily discomfort were noted. Study 2: Cognitive functioning was assessed to be Below Average, with 43-62% of the participants demonstrating significant impairments. Neuropsychological functioning yielded significant weakness on language functioning, and mild weakness on visual-motor integration and executive functioning. Conclusion: While the majority of the participants demonstrate psychosocial resiliency, a subgroup present with difficulties suggesting the need for intervention. Cognitive/neuropsychological functioning suggests poorer functioning with patterns similar to other high-risk pediatric populations. These results are preliminary and further research on long-term psychosocial and neuropsychological development of pediatric heart transplant recipients is needed to better understand and ameliorate developmental trajectories.
AB - Background & Objectives: As more heart transplant recipients survive into late adolescence, research addressing long-term psychosocial and neurodevelopmental outcomes is imperative. The limited literature available suggests risk for psychosocial difficulties and lower cognitive, academic, and neuropsychological functioning. This paper reviews topic-related literature and provides preliminary data examining psychosocial and neuropsychological functioning of adolescents who received their heart transplant during infancy. Method: This paper offers a literature review AND presents preliminary data from studies conducted through Loma Linda University Children's Hospital (LLUCH). Study one examined psychosocial functioning and quality of life of adolescent infant heart transplant recipients. In study two, cognitive, academic, and neuropsychological data were analyzed. Results: Study 1: Overall psychosocial functioning fell in the Average range, however, a significant percentage of participants presented with difficulties on one or more of the psychosocial domains. Quality of life was also within normal limits, though concerns with general health and bodily discomfort were noted. Study 2: Cognitive functioning was assessed to be Below Average, with 43-62% of the participants demonstrating significant impairments. Neuropsychological functioning yielded significant weakness on language functioning, and mild weakness on visual-motor integration and executive functioning. Conclusion: While the majority of the participants demonstrate psychosocial resiliency, a subgroup present with difficulties suggesting the need for intervention. Cognitive/neuropsychological functioning suggests poorer functioning with patterns similar to other high-risk pediatric populations. These results are preliminary and further research on long-term psychosocial and neuropsychological development of pediatric heart transplant recipients is needed to better understand and ameliorate developmental trajectories.
KW - Cognition
KW - Neuropsychology
KW - Pediatric heart transplant
KW - Psychosocial
KW - Quality of life
KW - Self-esteem
KW - Social skills
KW - Intelligence
KW - Cognition Disorders/psychology
KW - Humans
KW - Infant
KW - Male
KW - Adolescent Development/physiology
KW - Neuropsychological Tests
KW - Self Concept
KW - Adolescent
KW - Quality of Life
KW - Female
KW - Adolescent Behavior
KW - Social Adjustment
KW - Interpersonal Relations
KW - Adaptation, Psychological
KW - Heart Transplantation/psychology
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UR - http://www.scopus.com/inward/citedby.url?scp=80054118438&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/f5b63825-e811-343e-b601-a59a3ddb16aa/
U2 - 10.2174/157340311797484277
DO - 10.2174/157340311797484277
M3 - Article
C2 - 22548035
SN - 1573-403X
VL - 7
SP - 123
EP - 134
JO - Current Cardiology Reviews
JF - Current Cardiology Reviews
IS - 2
ER -