Proteome analysis of hypoxic glioblastoma cells reveals sequential metabolic adaptation of one-carbon metabolic pathways

  • Kangling Zhang
  • , Pei Xu
  • , James L. Sowers
  • , Daniel F. Machuca
  • , Barsam Mirfattah
  • , Jason Herring
  • , Hui Tang
  • , Yan Chen
  • , Bing Tian
  • , Allan R. Brasier
  • , Lawrence C. Sowers

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1906-1921
Number of pages16
JournalMolecular and Cellular Proteomics
Volume16
Issue number11
DOIs
StatePublished - Nov 2017
Externally publishedYes

ASJC Scopus Subject Areas

  • Analytical Chemistry
  • Biochemistry
  • Molecular Biology

Keywords

  • Carbon/metabolism
  • Cell Proliferation
  • Humans
  • Gene Expression Regulation, Neoplastic
  • Neoplastic Stem Cells/metabolism
  • Tumor Microenvironment
  • Brain Neoplasms/metabolism
  • Histones/metabolism
  • Cell Hypoxia
  • Tandem Mass Spectrometry
  • Metabolic Networks and Pathways
  • Proteomics
  • Cell Line, Tumor
  • Chromatography, Liquid
  • Glycolysis
  • Proteome/genetics
  • Glioblastoma/metabolism
  • Transcobalamins/genetics

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