Progressive loss of EGFR in a subpopulation of breast cancers: Implications in target-directed therapeutics

Lee Yee Choong; Simin Lim; Marie Chiew-Shia Loh; Xiaohui Man; Yunhao Chen; Weiyi Toy; Mengfei Pan; Chien-Shing Chen; Anuradha Poonepalli; M Prakash Hande; Puay Hoon Tan; Manuel Salto-Tellez; Chow-Yin Wong; Nilesh Shah; Brian J Druker; Yoon-Pin Lim

Progressive loss of EGFR in a subpopulation of breast cancers: Implications in target-directed therapeutics

Lee Yee Choong, Simin Lim, Marie Chiew-Shia Loh, Xiaohui Man, Yunhao Chen, Weiyi Toy, Mengfei Pan, Chien-Shing Chen, Anuradha Poonepalli, M Prakash Hande, Puay Hoon Tan, Manuel Salto-Tellez, Chow-Yin Wong, Nilesh Shah, Brian J Druker, Yoon-Pin Lim

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Clinical Cancer Research
Volume	13
State	Published - Nov 15 2007

Disciplines

Medicine and Health Sciences
Oncology
Internal Medicine
Immunology and Infectious Disease

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@article{ef3ee47457be4a9ab66e96d793ca4392,

title = "Progressive loss of EGFR in a subpopulation of breast cancers: Implications in target-directed therapeutics",

author = "Choong, {Lee Yee} and Simin Lim and Loh, {Marie Chiew-Shia} and Xiaohui Man and Yunhao Chen and Weiyi Toy and Mengfei Pan and Chien-Shing Chen and Anuradha Poonepalli and Hande, {M Prakash} and Tan, {Puay Hoon} and Manuel Salto-Tellez and Chow-Yin Wong and Nilesh Shah and Druker, {Brian J} and Yoon-Pin Lim",

note = "AACR Centennial Conference: Translational Cancer Medicine-- Nov 4-8, 2007; Singapore B33 Understanding the molecular etiology and heterogeneity of disease has a direct impact on cancer therapeutics. To identify novel molecular changes associated with breast cancer progression, we conducted phosphoproteomics of the MCF10AT model comprising isogenic, ErbB2- and ErbB3-positive, xenograft-derived cell lines that mimic different stages of breast cancer.",

year = "2007",

month = nov,

day = "15",

language = "American English",

volume = "13",

journal = "Clinical Cancer Research",

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TY - JOUR

T1 - Progressive loss of EGFR in a subpopulation of breast cancers: Implications in target-directed therapeutics

AU - Choong, Lee Yee

AU - Lim, Simin

AU - Loh, Marie Chiew-Shia

AU - Man, Xiaohui

AU - Chen, Yunhao

AU - Toy, Weiyi

AU - Pan, Mengfei

AU - Chen, Chien-Shing

AU - Poonepalli, Anuradha

AU - Hande, M Prakash

AU - Tan, Puay Hoon

AU - Salto-Tellez, Manuel

AU - Wong, Chow-Yin

AU - Shah, Nilesh

AU - Druker, Brian J

AU - Lim, Yoon-Pin

N1 - AACR Centennial Conference: Translational Cancer Medicine-- Nov 4-8, 2007; Singapore B33 Understanding the molecular etiology and heterogeneity of disease has a direct impact on cancer therapeutics. To identify novel molecular changes associated with breast cancer progression, we conducted phosphoproteomics of the MCF10AT model comprising isogenic, ErbB2- and ErbB3-positive, xenograft-derived cell lines that mimic different stages of breast cancer.

PY - 2007/11/15

Y1 - 2007/11/15

UR - http://clincancerres.aacrjournals.org/content/13/22_Supplement/B33

M3 - Article

VL - 13

JO - Clinical Cancer Research

JF - Clinical Cancer Research

ER -

Progressive loss of EGFR in a subpopulation of breast cancers: Implications in target-directed therapeutics

Disciplines

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