Presenilin couples the paired phosphorylation of β-catenin independent of axin: Implications for β-catenin activation in tumorigenesis

David E. Kang; Salvador Soriano; Xuefeng Xia; Charles G. Eberhart; Bart De Strooper; Hui Zheng; Edward H. Koo

doi:10.1016/S0092-8674(02)00970-4

Presenilin couples the paired phosphorylation of β-catenin independent of axin: Implications for β-catenin activation in tumorigenesis

David E. Kang, Salvador Soriano, Xuefeng Xia, Charles G. Eberhart, Bart De Strooper, Hui Zheng, Edward H. Koo

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	751-762
Number of pages	12
Journal	Cell
Volume	110
Issue number	6
DOIs	https://doi.org/10.1016/S0092-8674(02)00970-4
State	Published - Sep 20 2002

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology

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@article{1e06a944603c49c89a09ffd412ab5419,

title = "Presenilin couples the paired phosphorylation of β-catenin independent of axin: Implications for β-catenin activation in tumorigenesis",

author = "Kang, {David E.} and Salvador Soriano and Xuefeng Xia and Eberhart, {Charles G.} and {De Strooper}, Bart and Hui Zheng and Koo, {Edward H.}",

note = "Funding Information: We thank Dr. Paul Robbins for gift of melanoma cell lines, Dr. S. Takada for Wnt-3a-transfected cells, Dr. F. Costantini for axin cDNA, Dr. A. Barth for mouse β-catenin cDNA, Dr. Christopher Salvadore (Cell Signaling) for phospho-β-catenin peptides, Dr. H. Land for pBABE-puro cDNA, Dr. H. Mori for PSN2 antibody, and Dr. J. Gleeson for helpful discussions. This work was supported by NIH NS28121 (E.H.K.), NS40039 (H.Z.), AHAF A2002-035 (S.S.), and 5T32 AG00216-10 (D.E.K.).",

year = "2002",

month = sep,

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doi = "10.1016/S0092-8674(02)00970-4",

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T1 - Presenilin couples the paired phosphorylation of β-catenin independent of axin

T2 - Implications for β-catenin activation in tumorigenesis

AU - Kang, David E.

AU - Soriano, Salvador

AU - Xia, Xuefeng

AU - Eberhart, Charles G.

AU - De Strooper, Bart

AU - Zheng, Hui

AU - Koo, Edward H.

N1 - Funding Information: We thank Dr. Paul Robbins for gift of melanoma cell lines, Dr. S. Takada for Wnt-3a-transfected cells, Dr. F. Costantini for axin cDNA, Dr. A. Barth for mouse β-catenin cDNA, Dr. Christopher Salvadore (Cell Signaling) for phospho-β-catenin peptides, Dr. H. Land for pBABE-puro cDNA, Dr. H. Mori for PSN2 antibody, and Dr. J. Gleeson for helpful discussions. This work was supported by NIH NS28121 (E.H.K.), NS40039 (H.Z.), AHAF A2002-035 (S.S.), and 5T32 AG00216-10 (D.E.K.).

PY - 2002/9/20

Y1 - 2002/9/20

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JO - Cell

JF - Cell

IS - 6

ER -

Presenilin couples the paired phosphorylation of β-catenin independent of axin: Implications for β-catenin activation in tumorigenesis

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