TY - JOUR
T1 - Posthemorrhagic hydrocephalus in low-birth-weight infants
T2 - Treatment by serial lumbar punctures
AU - Papile, Lu Ann
AU - Burstein, Jerome
AU - Burstein, Rochelle
AU - Koffler, Herbert
AU - Koops, Beverly L.
AU - Johnson, John D.
N1 - Funding Information:
From the Departments of Pediatrics and Radiolog~v, University of New Mexico School of Medicine. Supported in part b v National Institutes of Health Biomedical Research Support Grant (5S01RR05583) and a James Picker Foundation pilot research grant. Presented in part at the annual meeting of the Society for Pediatric Research, New York, N.Y., 1978. *Reprint address: Department of Pediatrics, University of New Mexico School of Medicine, A lbuqueque, NM 87131.
PY - 1980/8
Y1 - 1980/8
N2 - We have performed weekly computed tomographic brain scans on 28 surviving low-birth-weight infants with cerebral intraventricular hemorrhage and acute ventricular dilatation. Evolving hydrocephalus was observed in 15 infants. Twelve of the 15 infants were treated by removing large volumes of cerebrospinal fluid with serial lumbar punctures. Arrest in the progression of hydrocephalus was evident in 11 of the 12. Clinical hydrocephalus requiring surgical intervention occurred in one of the treated infants and in all three untreated infants. No complications of serial lumbar punctures were noted, whereas shunt-related morbidity was 100%. Our results suggest that serial lumbar punctures are effective in arresting the development of posthemorrhagic hydrocephalus.
AB - We have performed weekly computed tomographic brain scans on 28 surviving low-birth-weight infants with cerebral intraventricular hemorrhage and acute ventricular dilatation. Evolving hydrocephalus was observed in 15 infants. Twelve of the 15 infants were treated by removing large volumes of cerebrospinal fluid with serial lumbar punctures. Arrest in the progression of hydrocephalus was evident in 11 of the 12. Clinical hydrocephalus requiring surgical intervention occurred in one of the treated infants and in all three untreated infants. No complications of serial lumbar punctures were noted, whereas shunt-related morbidity was 100%. Our results suggest that serial lumbar punctures are effective in arresting the development of posthemorrhagic hydrocephalus.
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U2 - 10.1016/S0022-3476(80)80494-X
DO - 10.1016/S0022-3476(80)80494-X
M3 - Article
C2 - 7190604
SN - 0022-3476
VL - 97
SP - 273
EP - 277
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 2
ER -