Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: A cross-ancestry approach

Guimin Gao; Fangyuan Zhao; Thomas U. Ahearn; Kathryn L. Lunetta; Melissa A. Troester; Zhaohui Du; Temidayo O. Ogundiran; Oladosu Ojengbede; William Blot; Katherine L. Nathanson; Susan M. Domchek; Barbara Nemesure; Anselm Hennis; Stefan Ambs; Julian McClellan; Mark Nie; Kimberly Bertrand; Gary Zirpoli; Song Yao; Andrew F. Olshan; Jeannette T. Bensen; Elisa V. Bandera; Sarah Nyante; David V. Conti; Michael F. Press; Sue A. Ingles; Esther M. John; Leslie Bernstein; Jennifer J. Hu; Sandra L. Deming-Halverson; Stephen J. Chanock; Regina G. Ziegler; Jorge L. Rodriguez-Gil; Lara E. Sucheston-Campbell; Dale P. Sandler; Jack A. Taylor; Cari M. Kitahara; Katie M. O'Brien; Manjeet K. Bolla; Joe Dennis; Alison M. Dunning; Douglas F. Easton; Kyriaki Michailidou; Paul D.P. Pharoah; Qin Wang; Jonine Figueroa; Richard Biritwum; Ernest Adjei; Seth Wiafe; Christine B. Ambrosone; Wei Zheng; Olufunmilayo I. Olopade; Montserrat García-Closas; Julie R. Palmer; Christopher A. Haiman; Dezheng Huo

doi:10.1093/hmg/ddac102

Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: A cross-ancestry approach

Guimin Gao, Fangyuan Zhao, Thomas U. Ahearn, Kathryn L. Lunetta, Melissa A. Troester, Zhaohui Du, Temidayo O. Ogundiran, Oladosu Ojengbede, William Blot, Katherine L. Nathanson, Susan M. Domchek, Barbara Nemesure, Anselm Hennis, Stefan Ambs, Julian McClellan, Mark Nie, Kimberly Bertrand, Gary Zirpoli, Song Yao, Andrew F. OlshanJeannette T. Bensen, Elisa V. Bandera, Sarah Nyante, David V. Conti, Michael F. Press, Sue A. Ingles, Esther M. John, Leslie Bernstein, Jennifer J. Hu, Sandra L. Deming-Halverson, Stephen J. Chanock, Regina G. Ziegler, Jorge L. Rodriguez-Gil, Lara E. Sucheston-Campbell, Dale P. Sandler, Jack A. Taylor, Cari M. Kitahara, Katie M. O'Brien, Manjeet K. Bolla, Joe Dennis, Alison M. Dunning, Douglas F. Easton, Kyriaki Michailidou, Paul D.P. Pharoah, Qin Wang, Jonine Figueroa, Richard Biritwum, Ernest Adjei, Seth Wiafe, Christine B. Ambrosone, Wei Zheng, Olufunmilayo I. Olopade, Montserrat García-Closas, Julie R. Palmer, Christopher A. Haiman, Dezheng Huo

School of Public Health

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3133-3143
Number of pages	11
Journal	Human Molecular Genetics
Volume	31
Issue number	18
DOIs	https://doi.org/10.1093/hmg/ddac102
State	Published - Sep 15 2022

ASJC Scopus Subject Areas

Molecular Biology
Genetics
Genetics(clinical)

Keywords

Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Risk Factors
Female
Breast Neoplasms/genetics
Multifactorial Inheritance/genetics
Receptors, Estrogen/genetics

Access to Document

10.1093/hmg/ddac102

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Gao, G., Zhao, F., Ahearn, T. U., Lunetta, K. L., Troester, M. A., Du, Z., Ogundiran, T. O., Ojengbede, O., Blot, W., Nathanson, K. L., Domchek, S. M., Nemesure, B., Hennis, A., Ambs, S., McClellan, J., Nie, M., Bertrand, K., Zirpoli, G., Yao, S., ... Huo, D. (2022). Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: A cross-ancestry approach. Human Molecular Genetics, 31(18), 3133-3143. https://doi.org/10.1093/hmg/ddac102

Gao, G, Zhao, F, Ahearn, TU, Lunetta, KL, Troester, MA, Du, Z, Ogundiran, TO, Ojengbede, O, Blot, W, Nathanson, KL, Domchek, SM, Nemesure, B, Hennis, A, Ambs, S, McClellan, J, Nie, M, Bertrand, K, Zirpoli, G, Yao, S, Olshan, AF, Bensen, JT, Bandera, EV, Nyante, S, Conti, DV, Press, MF, Ingles, SA, John, EM, Bernstein, L, Hu, JJ, Deming-Halverson, SL, Chanock, SJ, Ziegler, RG, Rodriguez-Gil, JL, Sucheston-Campbell, LE, Sandler, DP, Taylor, JA, Kitahara, CM, O'Brien, KM, Bolla, MK, Dennis, J, Dunning, AM, Easton, DF, Michailidou, K, Pharoah, PDP, Wang, Q, Figueroa, J, Biritwum, R, Adjei, E, Wiafe, S, Ambrosone, CB, Zheng, W, Olopade, OI, García-Closas, M, Palmer, JR, Haiman, CA & Huo, D 2022, 'Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: A cross-ancestry approach', Human Molecular Genetics, vol. 31, no. 18, pp. 3133-3143. https://doi.org/10.1093/hmg/ddac102

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AU - Ahearn, Thomas U.

AU - Lunetta, Kathryn L.

AU - Troester, Melissa A.

AU - Du, Zhaohui

AU - Ogundiran, Temidayo O.

AU - Ojengbede, Oladosu

AU - Blot, William

AU - Nathanson, Katherine L.

AU - Domchek, Susan M.

AU - Nemesure, Barbara

AU - Hennis, Anselm

AU - Ambs, Stefan

AU - McClellan, Julian

AU - Nie, Mark

AU - Bertrand, Kimberly

AU - Zirpoli, Gary

AU - Yao, Song

AU - Olshan, Andrew F.

AU - Bensen, Jeannette T.

AU - Bandera, Elisa V.

AU - Nyante, Sarah

AU - Conti, David V.

AU - Press, Michael F.

AU - Ingles, Sue A.

AU - John, Esther M.

AU - Bernstein, Leslie

AU - Hu, Jennifer J.

AU - Deming-Halverson, Sandra L.

AU - Chanock, Stephen J.

AU - Ziegler, Regina G.

AU - Rodriguez-Gil, Jorge L.

AU - Sucheston-Campbell, Lara E.

AU - Sandler, Dale P.

AU - Taylor, Jack A.

AU - Kitahara, Cari M.

AU - O'Brien, Katie M.

AU - Bolla, Manjeet K.

AU - Dennis, Joe

AU - Dunning, Alison M.

AU - Easton, Douglas F.

AU - Michailidou, Kyriaki

AU - Pharoah, Paul D.P.

AU - Wang, Qin

AU - Figueroa, Jonine

AU - Biritwum, Richard

AU - Adjei, Ernest

AU - Wiafe, Seth

AU - Ambrosone, Christine B.

AU - Zheng, Wei

AU - Olopade, Olufunmilayo I.

AU - García-Closas, Montserrat

AU - Palmer, Julie R.

AU - Haiman, Christopher A.

AU - Huo, Dezheng

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ER -

Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: A cross-ancestry approach

ASJC Scopus Subject Areas

Keywords

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