Plant-based cholera toxin B subunit-insulin/GAD fusion pro-teins suppress the development of autoimmune diabetes

TY - JOUR

T1 - Plant-based cholera toxin B subunit-insulin/GAD fusion pro-teins suppress the development of autoimmune diabetes

AU - Befus, N.

AU - Langridge, William H. R.

N1 - Insulin-dependent diabetes mellitus (IDDM) is a T lymphocyte mediated organ-specific autoimmune disease in which pancreatic islet inflammation (insulitis) destroys the insulin-producing β-cells leading to a permanent increase in blood sugar levels (hyperglycemia). Principal self antigens recognized by the T-cells are glutamic acid decarboxylase (GAD) and insulin (INS), with GAD being the initiating antigen.

PY - 2000

Y1 - 2000

UR - https://link.springer.com/article/10.1007/s001030050021

M3 - Article

VL - 43

JO - Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

JF - Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

ER -