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Phosphodiesterase inhibition attenuates alterations to the tight junction proteins occludin and ZO-1 in immunostimulated Caco-2 intestinal monolayers

  • Todd W. Costantini
  • , Jessica Deree
  • , William Loomis
  • , James G. Putnam
  • , Sunghyuk Choi
  • , Andrew Baird
  • , Brian P. Eliceiri
  • , Vishal Bansal
  • , Raul Coimbra

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)18-22
Number of pages5
JournalLife Sciences
Volume84
Issue number1-2
DOIs
StatePublished - Jan 2 2009

ASJC Scopus Subject Areas

  • General Biochemistry,Genetics and Molecular Biology
  • General Pharmacology, Toxicology and Pharmaceutics

Keywords

  • Caco-2 cells
  • Cytokines
  • Inflammation
  • Intestinal permeability
  • Occludin
  • Pentoxifylline
  • Phosphodiesterase inhibition
  • Shock
  • Tight junction
  • ZO-1

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