Pharmacological- and gene therapy-based inhibition of protein kinase Cα/β enhances cardiac contractility and attenuates heart failure

Michael Hambleton; Harvey Hahn; Sven T. Pleger; Matthew C. Kuhn; Raisa Klevitsky; Andrew N. Carr; Thomas F. Kimball; Timothy E. Hewett; Gerald W. Dorn; Walter J. Koch; Jeffery D. Molkentin

doi:10.1161/CIRCULATIONAHA.105.592550

Pharmacological- and gene therapy-based inhibition of protein kinase Cα/β enhances cardiac contractility and attenuates heart failure

Michael Hambleton
, Harvey Hahn
, Sven T. Pleger
, Matthew C. Kuhn
, Raisa Klevitsky
, Andrew N. Carr
, Thomas F. Kimball
, Timothy E. Hewett
, Gerald W. Dorn
, Walter J. Koch
, Jeffery D. Molkentin

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	574-582
Number of pages	9
Journal	Circulation
Volume	114
Issue number	6
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.105.592550
State	Published - Aug 2006
Externally published	Yes

ASJC Scopus Subject Areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

Keywords

Cardiomyopathy
Contractility
Heart failure
Protein kinase C

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10.1161/CIRCULATIONAHA.105.592550

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Hambleton, M., Hahn, H., Pleger, S. T., Kuhn, M. C., Klevitsky, R., Carr, A. N., Kimball, T. F., Hewett, T. E., Dorn, G. W., Koch, W. J., & Molkentin, J. D. (2006). Pharmacological- and gene therapy-based inhibition of protein kinase Cα/β enhances cardiac contractility and attenuates heart failure. Circulation, 114(6), 574-582. https://doi.org/10.1161/CIRCULATIONAHA.105.592550

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title = "Pharmacological- and gene therapy-based inhibition of protein kinase Cα/β enhances cardiac contractility and attenuates heart failure",

keywords = "Cardiomyopathy, Contractility, Heart failure, Protein kinase C",

author = "Michael Hambleton and Harvey Hahn and Pleger, \{Sven T.\} and Kuhn, \{Matthew C.\} and Raisa Klevitsky and Carr, \{Andrew N.\} and Kimball, \{Thomas F.\} and Hewett, \{Timothy E.\} and Dorn, \{Gerald W.\} and Koch, \{Walter J.\} and Molkentin, \{Jeffery D.\}",

year = "2006",

month = aug,

doi = "10.1161/CIRCULATIONAHA.105.592550",

language = "English",

volume = "114",

pages = "574--582",

journal = "Circulation",

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T1 - Pharmacological- and gene therapy-based inhibition of protein kinase Cα/β enhances cardiac contractility and attenuates heart failure

AU - Hambleton, Michael

AU - Hahn, Harvey

AU - Pleger, Sven T.

AU - Kuhn, Matthew C.

AU - Klevitsky, Raisa

AU - Carr, Andrew N.

AU - Kimball, Thomas F.

AU - Hewett, Timothy E.

AU - Dorn, Gerald W.

AU - Koch, Walter J.

AU - Molkentin, Jeffery D.

PY - 2006/8

Y1 - 2006/8

KW - Cardiomyopathy

KW - Contractility

KW - Heart failure

KW - Protein kinase C

UR - https://www.scopus.com/pages/publications/33746799599

UR - https://www.scopus.com/pages/publications/33746799599#tab=citedBy

U2 - 10.1161/CIRCULATIONAHA.105.592550

DO - 10.1161/CIRCULATIONAHA.105.592550

M3 - Article

C2 - 16880328

AN - SCOPUS:33746799599

SN - 0009-7322

VL - 114

SP - 574

EP - 582

JO - Circulation

JF - Circulation

IS - 6

ER -

Pharmacological- and gene therapy-based inhibition of protein kinase Cα/β enhances cardiac contractility and attenuates heart failure

ASJC Scopus Subject Areas

Keywords

Access to Document

OpenUrl availability

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