Particles released from the Gyro C1E3 during simulated extracorporeal circulation

Tamaki Takano; Kin ichi Nakata; Sebastian Schulte-Eistrup; Shinji Kawahito; Julie Glueck; Ian C. Clarke; Paul Allen Williams; Tomohiro Maeda; Kenji Nonaka; Joerg Linneweber; Masaharu Yoshikawa; Akira Fujisawa; Kenzo Makinouchi; Michihiro Yokokawa; Yukihiko Nosé

doi:10.1046/j.1525-1594.2000.06628.x

Particles released from the Gyro C1E3 during simulated extracorporeal circulation

Tamaki Takano
, Kin ichi Nakata
, Sebastian Schulte-Eistrup
, Shinji Kawahito
, Julie Glueck
, Ian C. Clarke
, Paul Allen Williams
, Tomohiro Maeda
, Kenji Nonaka
, Joerg Linneweber
, Masaharu Yoshikawa
, Akira Fujisawa
, Kenzo Makinouchi
, Michihiro Yokokawa
, Yukihiko Nosé

Research output: Contribution to journal › Article › peer-review

Abstract

Evaluation of released particles from the blood pump during extracorporeal circulation is an important aspect because the particles may cause microembolism. The Gyro C1E3 is a centrifugal blood pump that has an impeller suspended by double pivot bearings inside the housing; therefore, it is important to evaluate the released particles. The C1E3 was driven for 14 days to simulate clinical left ventricular assist device (LVAD) and percutaneous cardiopulmonary support (PCPS). Also, a roller pump was driven for 2 days as a comparison. Released particles were weighed and examined by SEM. After 14 days of pumping, the particles from the C1E3 were 238.6 μg in an LVAD condition. The particles with the roller pump were 270.2 μg after only 2 days. Average particle sizes with the roller pump and C1E3 were 3.7 and 0.6 μm, respectively. These results suggest that the Gyro C1E3 substantially reduces the risk of microembolism from released particles.

Original language	English
Pages (from-to)	446-449
Number of pages	4
Journal	Artificial Organs
Volume	24
Issue number	6
DOIs	https://doi.org/10.1046/j.1525-1594.2000.06628.x
State	Published - Jun 2000

ASJC Scopus Subject Areas

Bioengineering
Medicine (miscellaneous)
Biomaterials
Biomedical Engineering

Keywords

Centrifugal pump
Left ventricular assist device
Micro particle release
Percutaneous cardiopulmonary support
Roller pump
Spallation
Extracorporeal Circulation/instrumentation
Microscopy, Electron, Scanning
Embolism/etiology
Centrifugation
Humans
Equipment Design
Particle Size
Biocompatible Materials
Heart-Assist Devices

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Takano, T., Nakata, K. I., Schulte-Eistrup, S., Kawahito, S., Glueck, J., Clarke, I. C., Williams, P. A., Maeda, T., Nonaka, K., Linneweber, J., Yoshikawa, M., Fujisawa, A., Makinouchi, K., Yokokawa, M., & Nosé, Y. (2000). Particles released from the Gyro C1E3 during simulated extracorporeal circulation. Artificial Organs, 24(6), 446-449. https://doi.org/10.1046/j.1525-1594.2000.06628.x

Takano, T, Nakata, KI, Schulte-Eistrup, S, Kawahito, S, Glueck, J, Clarke, IC, Williams, PA, Maeda, T, Nonaka, K, Linneweber, J, Yoshikawa, M, Fujisawa, A, Makinouchi, K, Yokokawa, M & Nosé, Y 2000, 'Particles released from the Gyro C1E3 during simulated extracorporeal circulation', Artificial Organs, vol. 24, no. 6, pp. 446-449. https://doi.org/10.1046/j.1525-1594.2000.06628.x

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abstract = "Evaluation of released particles from the blood pump during extracorporeal circulation is an important aspect because the particles may cause microembolism. The Gyro C1E3 is a centrifugal blood pump that has an impeller suspended by double pivot bearings inside the housing; therefore, it is important to evaluate the released particles. The C1E3 was driven for 14 days to simulate clinical left ventricular assist device (LVAD) and percutaneous cardiopulmonary support (PCPS). Also, a roller pump was driven for 2 days as a comparison. Released particles were weighed and examined by SEM. After 14 days of pumping, the particles from the C1E3 were 238.6 μg in an LVAD condition. The particles with the roller pump were 270.2 μg after only 2 days. Average particle sizes with the roller pump and C1E3 were 3.7 and 0.6 μm, respectively. These results suggest that the Gyro C1E3 substantially reduces the risk of microembolism from released particles.",

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AU - Nakata, Kin ichi

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AU - Glueck, Julie

AU - Clarke, Ian C.

AU - Williams, Paul Allen

AU - Maeda, Tomohiro

AU - Nonaka, Kenji

AU - Linneweber, Joerg

AU - Yoshikawa, Masaharu

AU - Fujisawa, Akira

AU - Makinouchi, Kenzo

AU - Yokokawa, Michihiro

AU - Nosé, Yukihiko

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AB - Evaluation of released particles from the blood pump during extracorporeal circulation is an important aspect because the particles may cause microembolism. The Gyro C1E3 is a centrifugal blood pump that has an impeller suspended by double pivot bearings inside the housing; therefore, it is important to evaluate the released particles. The C1E3 was driven for 14 days to simulate clinical left ventricular assist device (LVAD) and percutaneous cardiopulmonary support (PCPS). Also, a roller pump was driven for 2 days as a comparison. Released particles were weighed and examined by SEM. After 14 days of pumping, the particles from the C1E3 were 238.6 μg in an LVAD condition. The particles with the roller pump were 270.2 μg after only 2 days. Average particle sizes with the roller pump and C1E3 were 3.7 and 0.6 μm, respectively. These results suggest that the Gyro C1E3 substantially reduces the risk of microembolism from released particles.

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KW - Embolism/etiology

KW - Centrifugation

KW - Humans

KW - Equipment Design

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KW - Biocompatible Materials

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Particles released from the Gyro C1E3 during simulated extracorporeal circulation

Abstract

ASJC Scopus Subject Areas

Keywords

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