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Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C

  • Paul J. Pockros
  • , Eugene R. Schiff
  • , Mitchell L. Shiffman
  • , John G. McHutchison
  • , Robert G. Gish
  • , Nezam H. Afdhal
  • , Manana Makhviladze
  • , Mira Huyghe
  • , David Hecht
  • , Tilman Oltersdorf
  • , David A. Shapiro

Research output: Contribution to journal › Article › peer-review

Original languageEnglish
Pages (from-to)324-329
Number of pages6
JournalHepatology
Volume46
Issue number2
DOIs
StatePublished - Aug 2007
Externally publishedYes

ASJC Scopus Subject Areas

  • Hepatology

Keywords

  • Double-Blind Method
  • Administration, Oral
  • Humans
  • Middle Aged
  • Alanine Transaminase/blood
  • Apoptosis/drug effects
  • Male
  • Caspase Inhibitors
  • RNA, Viral/blood
  • Aspartate Aminotransferases/blood
  • Enzyme Inhibitors/therapeutic use
  • Female
  • Hepatitis C, Chronic/drug therapy
  • Pentanoic Acids/administration & dosage

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