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Nutrition and physical activity and chronic disease prevention: Research strategies and recommendations

  • Ross L. Prentice
  • , Walter C. Willet
  • , Peter Greenwald
  • , David Alberts
  • , Leslie Bernstein
  • , Norman F. Boyd
  • , Tim Byers
  • , Steven K. Clinton
  • , Gary Fraser
  • , Laurence Freedman
  • , David Hunter
  • , Victor Kipnis
  • , Laurence N. Kolonel
  • , Bruce S. Kristal
  • , Alan Kristal
  • , Johanna W. Lampe
  • , Anne McTiernan
  • , John Milner
  • , Ruth E. Patterson
  • , John D. Potter
  • Elio Riboli, Arthur Schatzkin, Allison Yates, Elizabeth Yetley

    Research output: Contribution to journal › Comment/debate › peer-review

    Abstract

    A shortage of credible information exists on practical dietary and physical activity patterns that have potential to reverse the national obesity epidemic and reduce the risk of major cancers and other chronic diseases. Securing such information is a challenging task, and there is considerable diversity of opinion concerning related research designs and priorities. Here, we put forward some perspectives on useful methodology and infrastructure developments for progress in this important area, and we list high-priority research topics in the areas of 1) assessment of nutrient intake and energy expenditure; 2) development of intermediate outcome biomarkers; 3) enhancement of cohort and cross-cultural studies; and 4) criteria for and development of full-scale nutrition and physical activity intervention trials. © Oxford University Press 2004, all rights reserved.
    Original languageEnglish
    Pages (from-to)1276-1287
    Number of pages12
    JournalJournal of the National Cancer Institute
    Volume96
    Issue number17
    DOIs
    StatePublished - Sep 1 2004

    ASJC Scopus Subject Areas

    • Oncology
    • Cancer Research

    Keywords

    • Primary Prevention/methods
    • Humans
    • Nutritional Physiological Phenomena
    • Feeding Behavior
    • Controlled Clinical Trials as Topic
    • Motor Activity
    • Energy Intake
    • Case-Control Studies
    • Cross-Cultural Comparison
    • Energy Metabolism
    • Obesity/complications
    • Biomarkers/blood
    • Outcome Assessment, Health Care
    • Chronic Disease
    • Research Design
    • Cohort Studies

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