TY - JOUR
T1 - Novel GLP-1R/GIPR co-agonist “twincretin” is neuroprotective in cell and rodent models of mild traumatic brain injury
AU - Tamargo, Ian A.
AU - Bader, Miaad
AU - Li, Yazhou
AU - Yu, Seong Jin
AU - Wang, Yun
AU - Talbot, Konrad
AU - DiMarchi, Richard D.
AU - Pick, Chaim G.
AU - Greig, Nigel H.
N1 - Publisher Copyright:
© 2016
PY - 2017/2/1
Y1 - 2017/2/1
KW - Glucagon-like peptide-1
KW - Glucose-dependent insulinotropic peptide
KW - Incretin
KW - Incretin mimetic
KW - Neurodegeneration
KW - Traumatic brain injury
KW - CREB-Binding Protein/metabolism
KW - Recognition, Psychology/drug effects
KW - Embryo, Mammalian
KW - Humans
KW - Male
KW - Receptors, Gastrointestinal Hormone/agonists
KW - Body Temperature/drug effects
KW - Neuroblastoma/pathology
KW - Brain Injuries, Traumatic/complications
KW - Incretins/therapeutic use
KW - Disease Models, Animal
KW - Reactive Oxygen Species/metabolism
KW - Glucagon-Like Peptide-1 Receptor/metabolism
KW - Neuroprotective Agents/therapeutic use
KW - Glucagon-Like Peptide 1/metabolism
KW - Cells, Cultured
KW - Rats
KW - Rats, Sprague-Dawley
KW - Signal Transduction/drug effects
KW - Mice, Inbred ICR
KW - Animals
KW - Memory Disorders/etiology
KW - Cell Line, Tumor
KW - Mice
KW - Maze Learning/drug effects
KW - Glucagon-Like Peptide-1 Receptor Agonists
UR - https://www.scopus.com/pages/publications/85002078883
UR - https://www.scopus.com/pages/publications/85002078883#tab=citedBy
UR - https://www.mendeley.com/catalogue/8e7317d5-a991-3b1c-8131-49f3e259ff3f/
U2 - 10.1016/j.expneurol.2016.11.005
DO - 10.1016/j.expneurol.2016.11.005
M3 - Article
C2 - 27845037
AN - SCOPUS:85002078883
SN - 0014-4886
VL - 288
SP - 176
EP - 186
JO - Experimental Neurology
JF - Experimental Neurology
ER -