TY - JOUR
T1 - Notch1 promotes the pro-osteogenic response of human aortic valve interstitial cells via modulation of erk1/2 and nuclear factor-κb activation
AU - Zeng, Qingchun
AU - Song, Rui
AU - Ao, Lihua
AU - Weyant, Michael J.
AU - Lee, Joon
AU - Xu, Dingli
AU - Fullerton, David A.
AU - Meng, Xianzhong
PY - 2013/7
Y1 - 2013/7
KW - Aortic valve
KW - Notch1
KW - Pro-osteogenic proteins
KW - Signal transduction
KW - Toll-like receptor 4
KW - Up-Regulation
KW - Phosphorylation
KW - Humans
KW - Middle Aged
KW - Male
KW - Intercellular Signaling Peptides and Proteins/metabolism
KW - Mitogen-Activated Protein Kinase 3/metabolism
KW - Bone Morphogenetic Protein 2/metabolism
KW - Transfection
KW - RNA Interference
KW - Time Factors
KW - Serrate-Jagged Proteins
KW - Calcinosis/enzymology
KW - Jagged-1 Protein
KW - Signal Transduction
KW - Cells, Cultured
KW - Lipopolysaccharides/pharmacology
KW - Mitogen-Activated Protein Kinase 1/metabolism
KW - Osteogenesis/drug effects
KW - Aortic Valve/drug effects
KW - Receptor, Notch1/genetics
KW - Aortic Valve Stenosis/enzymology
KW - Calcium-Binding Proteins/metabolism
KW - Membrane Proteins/metabolism
KW - Toll-Like Receptor 4/metabolism
KW - Aged
KW - Enzyme Activation
KW - NF-kappa B/metabolism
KW - Alkaline Phosphatase/metabolism
UR - https://www.scopus.com/pages/publications/84879085837
UR - https://www.scopus.com/pages/publications/84879085837#tab=citedBy
UR - https://www.mendeley.com/catalogue/a0cc8832-40fa-30b0-a81f-5ec4d569014e/
U2 - 10.1161/ATVBAHA.112.300912
DO - 10.1161/ATVBAHA.112.300912
M3 - Article
C2 - 23640488
AN - SCOPUS:84879085837
SN - 1079-5642
VL - 33
SP - 1580
EP - 1590
JO - Arteriosclerosis, Thrombosis, and Vascular Biology
JF - Arteriosclerosis, Thrombosis, and Vascular Biology
IS - 7
ER -