TY - JOUR
T1 - Multimodality Imaging in Aortic Stenosis
T2 - Beyond the Valve - Focusing on the Myocardium
AU - Gaznabi, Safwan
AU - Miranda, Jeirym
AU - Lorenzatti, Daniel
AU - Piña, Pamela
AU - Balasubramanian, Senthil S.
AU - Desai, Darshi
AU - Desai, Aditya
AU - Ho, Edwin C.
AU - Scotti, Andrea
AU - Gongora, Carlos A.
AU - Schenone, Aldo L.
AU - Garcia, Mario J.
AU - Latib, Azeem
AU - Parwani, Purvi
AU - Slipczuk, Leandro
N1 - Copyright © 2023 Elsevier Inc. All rights reserved.
PY - 2023/10
Y1 - 2023/10
N2 - Current guidelines of aortic stenosis (AS) management focus on valve parameters, LV systolic dysfunction, and symptoms; however, emerging data suggest that there may be benefit of aortic valve replacement before it becomes severe by present criteria. Myocardial assessment using novel multimodality imaging techniques exhibits subclinical myocardial injury and remodeling at various stages before guideline-directed interventions, which predicts adverse outcomes. This raises the question of whether implementing serial myocardial assessment should become part of the standard appraisal, thereby identifying high-risk patients aiming to minimize adverse outcomes.
AB - Current guidelines of aortic stenosis (AS) management focus on valve parameters, LV systolic dysfunction, and symptoms; however, emerging data suggest that there may be benefit of aortic valve replacement before it becomes severe by present criteria. Myocardial assessment using novel multimodality imaging techniques exhibits subclinical myocardial injury and remodeling at various stages before guideline-directed interventions, which predicts adverse outcomes. This raises the question of whether implementing serial myocardial assessment should become part of the standard appraisal, thereby identifying high-risk patients aiming to minimize adverse outcomes.
KW - Aortic stenosis
KW - Asymptomatic
KW - Discordant
KW - Fibrosis
KW - Global longitudinal strain
KW - Low flow low gradient
KW - Myocardium
KW - Aortic Valve Stenosis/diagnostic imaging
KW - Multimodal Imaging
KW - Humans
UR - https://www.scopus.com/pages/publications/85164325334
UR - https://www.scopus.com/pages/publications/85164325334#tab=citedBy
UR - https://www.mendeley.com/catalogue/8abc7103-be56-341c-b2a1-11965ac6375e/
U2 - 10.1016/j.hfc.2023.05.010
DO - 10.1016/j.hfc.2023.05.010
M3 - Review article
C2 - 37714589
AN - SCOPUS:85164325334
SN - 1551-7136
VL - 19
SP - 491
EP - 504
JO - Heart Failure Clinics
JF - Heart Failure Clinics
IS - 4
ER -