TY - JOUR
T1 - Multimodality Imaging in Aortic Stenosis
T2 - Beyond the Valve - Focusing on the Myocardium
AU - Gaznabi, Safwan
AU - Miranda, Jeirym
AU - Lorenzatti, Daniel
AU - Piña, Pamela
AU - Balasubramanian, Senthil S.
AU - Desai, Darshi
AU - Desai, Aditya
AU - Ho, Edwin C.
AU - Scotti, Andrea
AU - Gongora, Carlos A.
AU - Schenone, Aldo L.
AU - Garcia, Mario J.
AU - Latib, Azeem
AU - Parwani, Purvi
AU - Slipczuk, Leandro
N1 - Copyright © 2024 Elsevier Inc. All rights reserved.
PY - 2024/8
Y1 - 2024/8
N2 - Current guidelines of aortic stenosis (AS) management focus on valve parameters, LV systolic dysfunction, and symptoms; however, emerging data suggest that there may be benefit of aortic valve replacement before it becomes severe by present criteria. Myocardial assessment using novel multimodality imaging techniques exhibits subclinical myocardial injury and remodeling at various stages before guideline-directed interventions, which predicts adverse outcomes. This raises the question of whether implementing serial myocardial assessment should become part of the standard appraisal, thereby identifying high-risk patients aiming to minimize adverse outcomes.
AB - Current guidelines of aortic stenosis (AS) management focus on valve parameters, LV systolic dysfunction, and symptoms; however, emerging data suggest that there may be benefit of aortic valve replacement before it becomes severe by present criteria. Myocardial assessment using novel multimodality imaging techniques exhibits subclinical myocardial injury and remodeling at various stages before guideline-directed interventions, which predicts adverse outcomes. This raises the question of whether implementing serial myocardial assessment should become part of the standard appraisal, thereby identifying high-risk patients aiming to minimize adverse outcomes.
KW - Aortic stenosis
KW - Asymptomatic
KW - Discordant
KW - Fibrosis
KW - Global longitudinal strain
KW - Low flow low gradient
KW - Myocardium
KW - Humans
KW - Multimodal Imaging/methods
KW - Magnetic Resonance Imaging, Cine/methods
KW - Aortic Valve Stenosis/diagnostic imaging
KW - Myocardium/pathology
KW - Aortic Valve/diagnostic imaging
UR - https://www.scopus.com/pages/publications/85196426498
UR - https://www.scopus.com/pages/publications/85196426498#tab=citedBy
UR - https://www.mendeley.com/catalogue/4a625a38-546b-31c4-b26f-f38f521871cd/
U2 - 10.1016/j.ccl.2024.04.002
DO - 10.1016/j.ccl.2024.04.002
M3 - Review article
C2 - 38910026
AN - SCOPUS:85196426498
SN - 0733-8651
VL - 42
SP - 433
EP - 446
JO - Cardiology Clinics
JF - Cardiology Clinics
IS - 3
ER -